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. 2001 Jan-Feb;7(1):82–91. doi: 10.3201/eid0701.010113

Gastroenteritis in sentinel general practices,The Netherlands.

M A de Wit 1, M P Koopmans 1, L M Kortbeek 1, N J van Leeuwen 1, A I Bartelds 1, Y T van Duynhoven 1
PMCID: PMC2631671  PMID: 11266298

Abstract

From 1996 to 1999, the incidence of gastroenteritis in general practices and the role of a broad range of pathogens in the Netherlands were studied. All patients with gastroenteritis who had visited a general practitioner were reported. All patients who had visited a general practitioner for gastroenteritis (cases) and an equal number of patients visiting for nongastrointestinal symptoms (controls) were invited to participate in a case-control study. The incidence of gastroenteritis was 79.7 per 10,000 person years. Campylobacter was detected most frequently (10% of cases), followed by Giardia lamblia (5%), rotavirus (5%), Norwalk-like viruses (5%) and Salmonella (4%). Our study found that in the Netherlands (population 15.6 million), an estimated 128,000 persons each year consult their general practitioner for gastroenteritis, slightly less than in a comparable study in 1992 to 1993. A pathogen could be detected in almost 40% of patients (bacteria 16%, viruses 15%, parasites 8%).

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Selected References

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  1. Bern C., Martines J., de Zoysa I., Glass R. I. The magnitude of the global problem of diarrhoeal disease: a ten-year update. Bull World Health Organ. 1992;70(6):705–714. [PMC free article] [PubMed] [Google Scholar]
  2. Borgdorff M. W., Koopmans M. P., Goosen E. S., Sprenger M. J. Surveillance of gastroenteritis. Lancet. 1995 Sep 23;346(8978):842–843. [PubMed] [Google Scholar]
  3. Guerrant R. L., Hughes J. M., Lima N. L., Crane J. Diarrhea in developed and developing countries: magnitude, special settings, and etiologies. Rev Infect Dis. 1990 Jan-Feb;12 (Suppl 1):S41–S50. doi: 10.1093/clinids/12.Supplement_1.S41. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Hoogenboom-Verdegaal A. M., de Jong J. C., During M., Hoogenveen R., Hoekstra J. A. Community-based study of the incidence of gastrointestinal diseases in The Netherlands. Epidemiol Infect. 1994 Jun;112(3):481–487. doi: 10.1017/s0950268800051189. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Koopmans M., Van Asperen I. Epidemiology of rotavirus infections in The Netherlands. Acta Paediatr Suppl. 1999 Jan;88(426):31–37. doi: 10.1111/j.1651-2227.1999.tb14323.x. [DOI] [PubMed] [Google Scholar]
  6. Mank T. G., Zaat J. O., Blotkamp J., Polderman A. M. Comparison of fresh versus sodium acetate acetic acid formalin preserved stool specimens for diagnosis of intestinal protozoal infections. Eur J Clin Microbiol Infect Dis. 1995 Dec;14(12):1076–1081. doi: 10.1007/BF01590942. [DOI] [PubMed] [Google Scholar]
  7. Mead P. S., Slutsker L., Dietz V., McCaig L. F., Bresee J. S., Shapiro C., Griffin P. M., Tauxe R. V. Food-related illness and death in the United States. Emerg Infect Dis. 1999 Sep-Oct;5(5):607–625. doi: 10.3201/eid0505.990502. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Monto A. S., Koopman J. S. The Tecumseh Study. XI. Occurrence of acute enteric illness in the community. Am J Epidemiol. 1980 Sep;112(3):323–333. doi: 10.1093/oxfordjournals.aje.a112998. [DOI] [PubMed] [Google Scholar]
  9. Palmer S., Houston H., Lervy B., Ribeiro D., Thomas P. Problems in the diagnosis of foodborne infection in general practice. Epidemiol Infect. 1996 Dec;117(3):479–484. doi: 10.1017/s0950268800059148. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Roderick P., Wheeler J., Cowden J., Sockett P., Skinner R., Mortimer P., Rowe B., Rodriques L. A pilot study of infectious intestinal disease in England. Epidemiol Infect. 1995 Apr;114(2):277–288. doi: 10.1017/s0950268800057940. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Sethi D., Wheeler J., Rodrigues L. C., Fox S., Roderick P. Investigation of under-ascertainment in epidemiological studies based in general practice. Int J Epidemiol. 1999 Feb;28(1):106–112. doi: 10.1093/ije/28.1.106. [DOI] [PubMed] [Google Scholar]
  12. Simpson G. E., Nagy G. S., Finckh E. S. A survey of acute gastro-enteritis in general practice. Med J Aust. 1969 Sep 27;2(13):633–635. [PubMed] [Google Scholar]
  13. Skirrow M. B. A demographic survey of campylobacter, salmonella and shigella infections in England. A Public Health Laboratory Service Survey. Epidemiol Infect. 1987 Dec;99(3):647–657. doi: 10.1017/s0950268800066504. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Smith H. R., Scotland S. M. ACP Broadsheet 135: January 1993. Isolation and identification methods for Escherichia coli O157 and other Vero cytotoxin producing strains. J Clin Pathol. 1993 Jan;46(1):10–17. doi: 10.1136/jcp.46.1.10. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Tompkins D. S., Hudson M. J., Smith H. R., Eglin R. P., Wheeler J. G., Brett M. M., Owen R. J., Brazier J. S., Cumberland P., King V. A study of infectious intestinal disease in England: microbiological findings in cases and controls. Commun Dis Public Health. 1999 Jun;2(2):108–113. [PubMed] [Google Scholar]
  16. Vinjé J., Altena S. A., Koopmans M. P. The incidence and genetic variability of small round-structured viruses in outbreaks of gastroenteritis in The Netherlands. J Infect Dis. 1997 Nov;176(5):1374–1378. doi: 10.1086/517325. [DOI] [PubMed] [Google Scholar]
  17. Vinjé J., Deijl H., van der Heide R., Lewis D., Hedlund K. O., Svensson L., Koopmans M. P. Molecular detection and epidemiology of Sapporo-like viruses. J Clin Microbiol. 2000 Feb;38(2):530–536. doi: 10.1128/jcm.38.2.530-536.2000. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Vinjé J., Koopmans M. P. Molecular detection and epidemiology of small round-structured viruses in outbreaks of gastroenteritis in the Netherlands. J Infect Dis. 1996 Sep;174(3):610–615. doi: 10.1093/infdis/174.3.610. [DOI] [PubMed] [Google Scholar]
  19. Wheeler J. G., Sethi D., Cowden J. M., Wall P. G., Rodrigues L. C., Tompkins D. S., Hudson M. J., Roderick P. J. Study of infectious intestinal disease in England: rates in the community, presenting to general practice, and reported to national surveillance. The Infectious Intestinal Disease Study Executive. BMJ. 1999 Apr 17;318(7190):1046–1050. doi: 10.1136/bmj.318.7190.1046. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Yang J., Scholten T. A fixative for intestinal parasites permitting the use of concentration and permanent staining procedures. Am J Clin Pathol. 1977 Mar;67(3):300–304. doi: 10.1093/ajcp/67.3.300. [DOI] [PubMed] [Google Scholar]
  21. de Wit M. A., Hoogenboom-Verdegaal A. M., Goosen E. S., Sprenger M. J., Borgdorff M. W. A population-based longitudinal study on the incidence and disease burden of gastroenteritis and Campylobacter and Salmonella infection in four regions of The Netherlands. Eur J Epidemiol. 2000;16(8):713–718. doi: 10.1023/a:1026754218713. [DOI] [PubMed] [Google Scholar]
  22. de Wit M. A., Koopmans M. P., van der Blij J. F., van Duynhoven Y. T. Hospital admissions for rotavirus infection in the Netherlands. Clin Infect Dis. 2000 Oct 4;31(3):698–704. doi: 10.1086/314025. [DOI] [PubMed] [Google Scholar]

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