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. 2001 Mar-Apr;7(2):277–281. doi: 10.3201/eid0702.010226

Biofilms and device-associated infections.

R M Donlan 1
PMCID: PMC2631701  PMID: 11294723

Abstract

Microorganisms commonly attach to living and nonliving surfaces, including those of indwelling medical devices, and form biofilms made up of extracellular polymers. In this state, microorganisms are highly resistant to antimicrobial treatment and are tenaciously bound to the surface. To better understand and control biofilms on indwelling medical devices, researchers should develop reliable sampling and measurement techniques, investigate the role of biofilms in antimicrobial drug resistance, and establish the link between biofilm contamination and patient infection.

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Selected References

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