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. 2001 Mar-Apr;7(2):259–262. doi: 10.3201/eid0702.010222

Tuberculosis control in the 21st century.

K A Sepkowitz 1
PMCID: PMC2631725  PMID: 11294719

Abstract

In response to tuberculosis (TB) outbreaks in the United States in the late 1980s and early 1990s, U.S. hospitals spent tremendous resources to ensure a safer workplace. A remarkable decrease in nosocomial transmission resulted, along with a decrease in TB cases nationally. Federal standards have been promulgated to ensure a safer work environment for all U.S. workers potentially exposed to TB. However, these measures may prove costly and burdensome and thus may compromise the ability to deliver care.

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Selected References

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  1. Adal K. A., Anglim A. M., Palumbo C. L., Titus M. G., Coyner B. J., Farr B. M. The use of high-efficiency particulate air-filter respirators to protect hospital workers from tuberculosis. A cost-effectiveness analysis. N Engl J Med. 1994 Jul 21;331(3):169–173. doi: 10.1056/NEJM199407213310306. [DOI] [PubMed] [Google Scholar]
  2. Behr M. A., Warren S. A., Salamon H., Hopewell P. C., Ponce de Leon A., Daley C. L., Small P. M. Transmission of Mycobacterium tuberculosis from patients smear-negative for acid-fast bacilli. Lancet. 1999 Feb 6;353(9151):444–449. doi: 10.1016/s0140-6736(98)03406-0. [DOI] [PubMed] [Google Scholar]
  3. Blumberg H. M. Tuberculosis and infection control: what now? Infect Control Hosp Epidemiol. 1997 Aug;18(8):538–541. doi: 10.1086/647668. [DOI] [PubMed] [Google Scholar]
  4. Blumberg H. M., Watkins D. L., Berschling J. D., Antle A., Moore P., White N., Hunter M., Green B., Ray S. M., McGowan J. E., Jr Preventing the nosocomial transmission of tuberculosis. Ann Intern Med. 1995 May 1;122(9):658–663. doi: 10.7326/0003-4819-122-9-199505010-00003. [DOI] [PubMed] [Google Scholar]
  5. Catanzaro A., Perry S., Clarridge J. E., Dunbar S., Goodnight-White S., LoBue P. A., Peter C., Pfyffer G. E., Sierra M. F., Weber R. The role of clinical suspicion in evaluating a new diagnostic test for active tuberculosis: results of a multicenter prospective trial. JAMA. 2000 Feb 2;283(5):639–645. doi: 10.1001/jama.283.5.639. [DOI] [PubMed] [Google Scholar]
  6. Cauthen G. M., Snider D. E., Jr, Onorato I. M. Boosting of tuberculin sensitivity among Southeast Asian refugees. Am J Respir Crit Care Med. 1994 Jun;149(6):1597–1600. doi: 10.1164/ajrccm.149.6.8004319. [DOI] [PubMed] [Google Scholar]
  7. FitzGerald J. M., Grzybowski S., Allen E. A. The impact of human immunodeficiency virus infection on tuberculosis and its control. Chest. 1991 Jul;100(1):191–200. doi: 10.1378/chest.100.1.191. [DOI] [PubMed] [Google Scholar]
  8. Fridkin S. K., Manangan L., Bolyard E., Jarvis W. R. SHEA-CDC TB survey, Part I: Status of TB infection control programs at member hospitals, 1989-1992. Society for Healthcare Epidemiology of America. Infect Control Hosp Epidemiol. 1995 Mar;16(3):129–134. doi: 10.1086/647073. [DOI] [PubMed] [Google Scholar]
  9. Fridkin S. K., Manangan L., Bolyard E., Jarvis W. R. SHEA-CDC TB survey, Part II: Efficacy of TB infection control programs at member hospitals, 1992. Society for Healthcare Epidemiology of America. Infect Control Hosp Epidemiol. 1995 Mar;16(3):135–140. doi: 10.1086/647074. [DOI] [PubMed] [Google Scholar]
  10. Grzybowski S., Barnett G. D., Styblo K. Contacts of cases of active pulmonary tuberculosis. Bull Int Union Tuberc. 1975;50(1):90–106. [PubMed] [Google Scholar]
  11. Horowitz H. W., Luciano B. B., Kadel J. R., Wormser G. P. Tuberculin skin test conversion in hospital employees vaccinated with bacille Calmette-Guérin: recent Mycobacterium tuberculosis infection or booster effect? Am J Infect Control. 1995 Jun;23(3):181–187. doi: 10.1016/0196-6553(95)90039-x. [DOI] [PubMed] [Google Scholar]
  12. Kamat S. R., Dawson J. J., Devadatta S., Fox W., Janardhanam B., Radhakrishna S., Ramakrishnan C. V., Somasundaram P. R., Stott H., Velu S. A controlled study of the influence of segregation of tuberculous patients for one year on the attack rate of tuberculosis in a 5-year period in close family contacts in South India. Bull World Health Organ. 1966;34(4):517–532. [PMC free article] [PubMed] [Google Scholar]
  13. Louther J., Rivera P., Feldman J., Villa N., DeHovitz J., Sepkowitz K. A. Risk of tuberculin conversion according to occupation among health care workers at a New York City hospital. Am J Respir Crit Care Med. 1997 Jul;156(1):201–205. doi: 10.1164/ajrccm.156.1.9611091. [DOI] [PubMed] [Google Scholar]
  14. McGowan J. E., Jr Nosocomial tuberculosis: new progress in control and prevention. Clin Infect Dis. 1995 Sep;21(3):489–505. doi: 10.1093/clinids/21.3.489. [DOI] [PubMed] [Google Scholar]
  15. Menzies D. Effect of treatment on contagiousness of patients with active pulmonary tuberculosis. Infect Control Hosp Epidemiol. 1997 Aug;18(8):582–586. doi: 10.1086/647678. [DOI] [PubMed] [Google Scholar]
  16. Menzies D., Fanning A., Yuan L., Fitzgerald M. Tuberculosis among health care workers. N Engl J Med. 1995 Jan 12;332(2):92–98. doi: 10.1056/NEJM199501123320206. [DOI] [PubMed] [Google Scholar]
  17. Menzies D. Interpretation of repeated tuberculin tests. Boosting, conversion, and reversion. Am J Respir Crit Care Med. 1999 Jan;159(1):15–21. doi: 10.1164/ajrccm.159.1.9801120. [DOI] [PubMed] [Google Scholar]
  18. Nettleman M. D., Fredrickson M., Good N. L., Hunter S. A. Tuberculosis control strategies: the cost of particulate respirators. Ann Intern Med. 1994 Jul 1;121(1):37–40. doi: 10.7326/0003-4819-121-1-199407010-00007. [DOI] [PubMed] [Google Scholar]
  19. Sepkowitz K. A. AIDS, tuberculosis, and the health care worker. Clin Infect Dis. 1995 Feb;20(2):232–242. doi: 10.1093/clinids/20.2.232. [DOI] [PubMed] [Google Scholar]
  20. Sepkowitz K. A. Tuberculosis and the health care worker: a historical perspective. Ann Intern Med. 1994 Jan 1;120(1):71–79. doi: 10.7326/0003-4819-120-1-199401010-00012. [DOI] [PubMed] [Google Scholar]
  21. Snider D. E., Jr, Cauthen G. M. Tuberculin skin testing of hospital employees: infection, "boosting," and two-step testing. Am J Infect Control. 1984 Dec;12(6):305–311. doi: 10.1016/0196-6553(84)90001-4. [DOI] [PubMed] [Google Scholar]

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