Abstract
On September 6, 2000, two cases of equine encephalitis caused by West Nile (WN) virus were reported in southern France (Hérault Province), near Camargue National Park, where a WN outbreak occurred in 1962. Through November 30, 76 cases were laboratory confirmed among 131 equines with neurologic disorders. The last confirmed case was on November 3, 2000. All but three cases were located in a region nicknamed "la petite Camargue," which has several large marshes, numerous colonies of migratory and resident birds, and large mosquito populations. No human case has been confirmed among clinically suspected patients, nor have abnormal deaths of birds been reported. A serosurvey has been undertaken in horses in the infected area, and other studies are in progress.
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- BERNKOPF H., LEVINE S., NERSON R. Isolation of West Nile virus in Israel. J Infect Dis. 1953 Nov-Dec;93(3):207–218. doi: 10.1093/infdis/93.3.207. [DOI] [PubMed] [Google Scholar]
- Berthet F. X., Zeller H. G., Drouet M. T., Rauzier J., Digoutte J. P., Deubel V. Extensive nucleotide changes and deletions within the envelope glycoprotein gene of Euro-African West Nile viruses. J Gen Virol. 1997 Sep;78(Pt 9):2293–2297. doi: 10.1099/0022-1317-78-9-2293. [DOI] [PubMed] [Google Scholar]
- Cantile C., Di Guardo G., Eleni C., Arispici M. Clinical and neuropathological features of West Nile virus equine encephalomyelitis in Italy. Equine Vet J. 2000 Jan;32(1):31–35. doi: 10.2746/042516400777612080. [DOI] [PubMed] [Google Scholar]
- Centers for Disease Control and Prevention (CDC) Update: Surveillance for West Nile virus in overwintering mosquitoes--New York, 2000. MMWR Morb Mortal Wkly Rep. 2000 Mar 10;49(9):178–179. [PubMed] [Google Scholar]
- Centers for Disease Control and Prevention (CDC) Update: West Nile Virus activity--Eastern United States, 2000. MMWR Morb Mortal Wkly Rep. 2000 Nov 24;49(46):1044–1047. [PubMed] [Google Scholar]
- Cernescu C., Nedelcu N. I., Tardei G., Ruta S., Tsai T. F. Continued transmission of West Nile virus to humans in southeastern Romania, 1997-1998. J Infect Dis. 2000 Feb;181(2):710–712. doi: 10.1086/315225. [DOI] [PubMed] [Google Scholar]
- HANNOUN C., PANTHIER R., MOUCHET J., EOUZAN J. P. ISOLEMENT EN FRANCE DU VIRUS WEST-NILE 'A PARTIR DE MALADES ET DU VECTEUR CULEX MODESTUS FICALBI. C R Hebd Seances Acad Sci. 1964 Nov 30;259:4170–4172. [PubMed] [Google Scholar]
- HURLBUT H. S., RIZK F., TAYLOR R. M., WORK T. H. A study of the ecology of West Nile virus in Egypt. Am J Trop Med Hyg. 1956 Jul;5(4):579–620. doi: 10.4269/ajtmh.1956.5.579. [DOI] [PubMed] [Google Scholar]
- Joubert L., Oudar J., Hannoun C., Beytout D., Corniou B., Guillon J. C., Panthier R. Epidémiologie du virus West Nile: etude d'un foyer en Camargue. IV. La méningo-encéphalomyélite du cheval. Ann Inst Pasteur (Paris) 1970 Feb;118(2):239–247. [PubMed] [Google Scholar]
- Joubert L., Oudar J., Hannoun C., Chippaux M. Reproduction expèrimentale de la mèningo-encèphalomyèlite du cheval par l'arbovirus West Nile. 3. Relations entre la virologie, la sèrologie et l'èvoliution anatomo-clinique. Consèquences èpidèmiologiques et prophylactiques. Bull Acad Vet Fr. 1971 Mar;44(3):159–167. [PubMed] [Google Scholar]
- Le Guenno B., Bougermouh A., Azzam T., Bouakaz R. West Nile: a deadly virus? Lancet. 1996 Nov 9;348(9037):1315–1315. doi: 10.1016/s0140-6736(05)65799-6. [DOI] [PubMed] [Google Scholar]
- Miller B. R., Nasci R. S., Godsey M. S., Savage H. M., Lutwama J. J., Lanciotti R. S., Peters C. J. First field evidence for natural vertical transmission of West Nile virus in Culex univittatus complex mosquitoes from Rift Valley province, Kenya. Am J Trop Med Hyg. 2000 Feb;62(2):240–246. doi: 10.4269/ajtmh.2000.62.240. [DOI] [PubMed] [Google Scholar]
- Novello A. C. West Nile virus in New York State: the 1999 outbreak and response plan for 2000. Viral Immunol. 2000;13(4):463–467. doi: 10.1089/vim.2000.13.463. [DOI] [PubMed] [Google Scholar]
- Oudar J., Joubert L., Lapras M., Guillon J. C. Reproduction expèrimentale de la mèningo-encèphalomyèlite du cheval par l'arbovirus West Nile. II. Etude anatomo-clinique. Bull Acad Vet Fr. 1971 Mar;44(3):147–158. [PubMed] [Google Scholar]
- Pantheir R., Hannoun C., Oudar J., Beytout D., Corniou B., Joubert L., Guillon J. C., Mouchet J. Isolement du virus West Nile chez un cheval de Camargue atteint d'encéphalomyélite. C R Acad Sci Hebd Seances Acad Sci D. 1966 Mar 14;262(11):1308–1310. [PubMed] [Google Scholar]
- Panthier R., Hannoun C., Beytout D., Mouchet J. Epidémiologie du virus west nile. Etudes d'un foyer en Camargue. 3.-Les maladies humaines. Ann Inst Pasteur (Paris) 1968 Sep;115(3):435–445. [PubMed] [Google Scholar]
- Platonov A. E., Shipulin G. A., Shipulina O. Y., Tyutyunnik E. N., Frolochkina T. I., Lanciotti R. S., Yazyshina S., Platonova O. V., Obukhov I. L., Zhukov A. N. Outbreak of West Nile virus infection, Volgograd Region, Russia, 1999. Emerg Infect Dis. 2001 Jan-Feb;7(1):128–132. doi: 10.3201/eid0701.010118. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rappole J. H., Derrickson S. R., Hubálek Z. Migratory birds and spread of West Nile virus in the Western Hemisphere. Emerg Infect Dis. 2000 Jul-Aug;6(4):319–328. doi: 10.3201/eid0604.000401. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SCHMIDT J. R., ELMANSOURY H. K. NATURAL AND EXPERIMENTAL INFECTION OF EGYPTIAN EQUINES WITH WEST NILE VIRUS. Ann Trop Med Parasitol. 1963 Dec;57:415–427. doi: 10.1080/00034983.1963.11686194. [DOI] [PubMed] [Google Scholar]
- Siegel-Itzkovich J. Twelve die of West Nile Virus in Israel. BMJ. 2000 Sep 23;321(7263):724–724. [PMC free article] [PubMed] [Google Scholar]
- Tsai T. F., Popovici F., Cernescu C., Campbell G. L., Nedelcu N. I. West Nile encephalitis epidemic in southeastern Romania. Lancet. 1998 Sep 5;352(9130):767–771. doi: 10.1016/s0140-6736(98)03538-7. [DOI] [PubMed] [Google Scholar]
- Zeller H. G., Fontenille D., Traore-Lamizana M., Thiongane Y., Digoutte J. P. Enzootic activity of Rift Valley fever virus in Senegal. Am J Trop Med Hyg. 1997 Mar;56(3):265–272. doi: 10.4269/ajtmh.1997.56.265. [DOI] [PubMed] [Google Scholar]
- Zeller H. G. West Nile: une arbovirose migrante d'actualité. Med Trop (Mars) 1999;59(4 Pt 2):490–494. [PubMed] [Google Scholar]
