Abstract
To identify risk factors and describe the pattern of spread of the 1997 cholera epidemic in a rural area (Ifakara) in southern Tanzania, we conducted a prospective hospital-based, matched case- control study, with analysis based on the first 180 cases and 360 matched controls. Bathing in the river, long distance to water source, and eating dried fish were significantly associated with risk for cholera. Toxigenic Vibrio cholerae O1, biotype El Tor, serotype Ogawa, was isolated in samples from Ifakara's main water source and patients' stools. DNA molecular analyses showed identical patterns for all isolates.
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- Birmingham M. E., Lee L. A., Ndayimirije N., Nkurikiye S., Hersh B. S., Wells J. G., Deming M. S. Epidemic cholera in Burundi: patterns of transmission in the Great Rift Valley Lake region. Lancet. 1997 Apr 5;349(9057):981–985. doi: 10.1016/S0140-6736(96)08478-4. [DOI] [PubMed] [Google Scholar]
- Cash R. A., Music S. I., Libonati J. P., Snyder M. J., Wenzel R. P., Hornick R. B. Response of man to infection with Vibrio cholerae. I. Clinical, serologic, and bacteriologic responses to a known inoculum. J Infect Dis. 1974 Jan;129(1):45–52. doi: 10.1093/infdis/129.1.45. [DOI] [PubMed] [Google Scholar]
- Hughes J. M., Boyce J. M., Levine R. J., Khan M., Aziz K. M., Huq M. I., Curlin G. T. Epidemiology of eltor cholera in rural Bangladesh: importance of surface water in transmission. Bull World Health Organ. 1982;60(3):395–404. [PMC free article] [PubMed] [Google Scholar]
- Rodrigues A., Brun H., Sandstrom A. Risk factors for cholera infection in the initial phase of an epidemic in Guinea-Bissau: protection by lime juice. Am J Trop Med Hyg. 1997 Nov;57(5):601–604. doi: 10.4269/ajtmh.1997.57.601. [DOI] [PubMed] [Google Scholar]
- Webber R. H., Mwakalukwa J. The epidemiology of cholera in south-west Tanzania. East Afr Med J. 1983 Dec;60(12):848–856. [PubMed] [Google Scholar]