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. 2001 Sep-Oct;7(5):872–876. doi: 10.3201/eid0705.017516

Topical insecticide treatments to protect dogs from sand fly vectors of leishmaniasis.

R Reithinger 1, U Teodoro 1, C R Davies 1
PMCID: PMC2631889  PMID: 11747701

Abstract

We compared the susceptibility of sand fly vectors to four topical insecticide treatments applied to domestic dogs, a reservoir of human leishmaniasis. Dogs were exposed to sand flies pretreatment and at 1 week, 1 month, and 2 months posttreatment. Sand fly bloodfeeding and survival rate of both fed and unfed flies were significantly reduced by the permethrin, deltamethrin, and fenthion treatments, but diazinon had no effect. The survival rate of bloodfed sand flies was reduced by up to 86% with deltamethrin collars. The antifeeding effect suggests that deltamethrin collars may be recommended to dog owners to protect their pets from sandfly- borne diseases. The combined effects on sand fly feeding and survival indicate that epidemiologic, community-based trials are warranted to test whether deltamethrin collars could reduce the incidence of canine and, hence, human leishmaniasis.

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Selected References

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  1. Alvar J., Cañavate C., Gutiérrez-Solar B., Jiménez M., Laguna F., López-Vélez R., Molina R., Moreno J. Leishmania and human immunodeficiency virus coinfection: the first 10 years. Clin Microbiol Rev. 1997 Apr;10(2):298–319. doi: 10.1128/cmr.10.2.298. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Arias J. R., Monteiro P. S., Zicker F. The reemergence of visceral leishmaniasis in Brazil. Emerg Infect Dis. 1996 Apr-Jun;2(2):145–146. doi: 10.3201/eid0202.960213. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Ashford D. A., David J. R., Freire M., David R., Sherlock I., Eulálio M. C., Sampaio D. P., Badaro R. Studies on control of visceral leishmaniasis: impact of dog control on canine and human visceral leishmaniasis in Jacobina, Bahia, Brazil. Am J Trop Med Hyg. 1998 Jul;59(1):53–57. doi: 10.4269/ajtmh.1998.59.53. [DOI] [PubMed] [Google Scholar]
  4. Ashford R. W. Leishmaniasis reservoirs and their significance in control. Clin Dermatol. 1996 Sep-Oct;14(5):523–532. doi: 10.1016/0738-081x(96)00041-7. [DOI] [PubMed] [Google Scholar]
  5. Campbell-Lendrum D. H., Pinto M. C., Brandão-Filho S. P., de Souza A. A., Ready P. D., Davies C. R. Experimental comparison of anthropophily between geographically dispersed populations of Lutzomyia whitmani (Diptera: Psychodidae). Med Vet Entomol. 1999 Jul;13(3):299–309. doi: 10.1046/j.1365-2915.1999.00174.x. [DOI] [PubMed] [Google Scholar]
  6. Dereure J., Rioux J. A., Gallego M., Perières J., Pratlong F., Mahjour J., Saddiki H. Leishmania tropica in Morocco: infection in dogs. Trans R Soc Trop Med Hyg. 1991 Sep-Oct;85(5):595–595. doi: 10.1016/0035-9203(91)90356-4. [DOI] [PubMed] [Google Scholar]
  7. Dietze R., Barros G. B., Teixeira L., Harris J., Michelson K., Falqueto A., Corey R. Effect of eliminating seropositive canines on the transmission of visceral leishmaniasis in Brazil. Clin Infect Dis. 1997 Nov;25(5):1240–1242. doi: 10.1086/516096. [DOI] [PubMed] [Google Scholar]
  8. Dye C. The logic of visceral leishmaniasis control. Am J Trop Med Hyg. 1996 Aug;55(2):125–130. doi: 10.4269/ajtmh.1996.55.125. [DOI] [PubMed] [Google Scholar]
  9. Gothe R., Nolte I., Kraft W. Leishmaniose des Hundes in Deutschland: epidemiologische Fallanalyse und Alternative zur bisherigen kausalen Therapie. Tierarztl Prax. 1997 Jan;25(1):68–73. [PubMed] [Google Scholar]
  10. Halbig P., Hodjati M. H., Mazloumi-Gavgani A. S., Mohite H., Davies C. R. Further evidence that deltamethrin-impregnated collars protect domestic dogs from sandfly bites. Med Vet Entomol. 2000 Jun;14(2):223–226. doi: 10.1046/j.1365-2915.2000.00229.x. [DOI] [PubMed] [Google Scholar]
  11. Killick-Kendrick R., Killick-Kendrick M., Focheux C., Dereure J., Puech M. P., Cadiergues M. C. Protection of dogs from bites of phlebotomine sandflies by deltamethrin collars for control of canine leishmaniasis. Med Vet Entomol. 1997 Apr;11(2):105–111. doi: 10.1111/j.1365-2915.1997.tb00298.x. [DOI] [PubMed] [Google Scholar]
  12. Marsella R. Advances in flea control. Vet Clin North Am Small Anim Pract. 1999 Nov;29(6):1407–1424. doi: 10.1016/s0195-5616(99)50135-6. [DOI] [PubMed] [Google Scholar]
  13. Reithinger R., Davies C. R. Is the domestic dog (Canis familiaris) a reservoir host of American cutaneous leishmaniasis? A critical review of the current evidence. Am J Trop Med Hyg. 1999 Oct;61(4):530–541. doi: 10.4269/ajtmh.1999.61.530. [DOI] [PubMed] [Google Scholar]
  14. Slappendel R. J., Teske E. The effect of intravenous or subcutaneous administration of meglumine antimonate (Glucantime) in dogs with leishmaniasis. A randomized clinical trial. Vet Q. 1997 Mar;19(1):10–13. doi: 10.1080/01652176.1997.9694729. [DOI] [PubMed] [Google Scholar]
  15. Tesh R. B. Control of zoonotic visceral leishmaniasis: is it time to change strategies? Am J Trop Med Hyg. 1995 Mar;52(3):287–292. doi: 10.4269/ajtmh.1995.52.287. [DOI] [PubMed] [Google Scholar]
  16. Vieira J. B., Coelho G. E. Leishmaniose visceral ou calazar: aspectos epidemiológicos e de controle. Rev Soc Bras Med Trop. 1998;31 (Suppl 2):85–92. [PubMed] [Google Scholar]

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