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. 1985 Feb;47(2):570–572. doi: 10.1128/iai.47.2.570-572.1985

Blastogenic response of bovine lymphocytes to Brucella abortus lipopolysaccharide.

C L Baldwin, A J Winter
PMCID: PMC263211  PMID: 3917981

Abstract

Brucella abortus lipopolysaccharide was tested in a blastogenesis assay with unfractionated and nylon wool-separated peripheral blood lymphocytes of Brucella-naive cattle and cattle immunized with B. abortus. Our results indicated that in cattle the lipopolysaccharide of B. abortus is not a B-cell mitogen. In immunized animals it stimulated predominantly nylon wool-adherent cells. The lipopolysaccharide of Escherichia coli O128:B12, in contrast, induced a substantially greater proliferative response in circulating lymphocytes, predominantly those adherent to nylon wool, of the Brucella-naive cattle.

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Selected References

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