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. 1984 Jul;45(1):276–277. doi: 10.1128/iai.45.1.276-277.1984

Examination of Haemophilus pleuropneumoniae for immunoglobulin A protease activity.

M H Mulks, E R Moxon, J Bricker, A Wright, A G Plaut
PMCID: PMC263313  PMID: 6329957

Abstract

Haemophilus pleuropneumoniae, the etiological agent of porcine contagious pneumonia, was examined for the ability to produce an immunoglobulin A (IgA) protease specific for porcine IgA. No IgA protease activity against either porcine or human IgA was detected. Furthermore, no sequence homology was found between H. pleuropneumoniae chromosomal DNA and the gene which specifies IgA protease in Haemophilus influenzae.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bricker J., Mulks M. H., Plaut A. G., Moxon E. R., Wright A. IgA1 proteases of Haemophilus influenzae: cloning and characterization in Escherichia coli K-12. Proc Natl Acad Sci U S A. 1983 May;80(9):2681–2685. doi: 10.1073/pnas.80.9.2681. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Doellgast G. J., Plaut A. G. Purification of human IgA by salt-mediated hydrophobic chromatography. Immunochemistry. 1976 Feb;13(2):135–139. doi: 10.1016/0019-2791(76)90281-0. [DOI] [PubMed] [Google Scholar]
  3. HUNTER W. M., GREENWOOD F. C. Preparation of iodine-131 labelled human growth hormone of high specific activity. Nature. 1962 May 5;194:495–496. doi: 10.1038/194495a0. [DOI] [PubMed] [Google Scholar]
  4. Kilian M., Mestecky J., Schrohenloher R. E. Pathogenic species of the genus Haemophilus and Streptococcus pneumoniae produce immunoglobulin A1 protease. Infect Immun. 1979 Oct;26(1):143–149. doi: 10.1128/iai.26.1.143-149.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Koomey J. M., Falkow S. Nucleotide sequence homology between the immunoglobulin A1 protease genes of Neisseria gonorrhoeae, Neisseria meningitidis, and Haemophilus influenzae. Infect Immun. 1984 Jan;43(1):101–107. doi: 10.1128/iai.43.1.101-107.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Kornfeld S. J., Plaut A. G. Secretory immunity and the bacterial IgA proteases. Rev Infect Dis. 1981 May-Jun;3(3):521–534. doi: 10.1093/clinids/3.3.521. [DOI] [PubMed] [Google Scholar]
  7. Lamm M. E., Greenberg J. Human secretory component. Comparison of the form occurring in exocrine immunoglobulin A to the free form. Biochemistry. 1972 Jul 18;11(15):2744–2750. doi: 10.1021/bi00765a002. [DOI] [PubMed] [Google Scholar]
  8. Little T. W. Haemophilus infection in pigs. Vet Rec. 1970 Oct 3;87(14):399–402. doi: 10.1136/vr.87.14.399. [DOI] [PubMed] [Google Scholar]
  9. Male C. J. Immunoglobulin A1 protease production by Haemophilus influenzae and Streptococcus pneumoniae. Infect Immun. 1979 Oct;26(1):254–261. doi: 10.1128/iai.26.1.254-261.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Mulks M. H., Kornfeld S. J., Frangione B., Plaut A. G. Relationship between the specificity of IgA proteases and serotypes in Haemophilus influenzae. J Infect Dis. 1982 Aug;146(2):266–274. doi: 10.1093/infdis/146.2.266. [DOI] [PubMed] [Google Scholar]
  11. Mulks M. H., Kornfeld S. J., Plaut A. G. Specific proteolysis of human IgA by Streptococcus pneumoniae and Haemophilus influenzae. J Infect Dis. 1980 Apr;141(4):450–456. doi: 10.1093/infdis/141.4.450. [DOI] [PubMed] [Google Scholar]
  12. SHOPE R. E. PORCINE CONTAGIOUS PLEUROPNEUMONIA. I. EXPERIMENTAL TRANSMISSION, ETIOLOGY, AND PATHOLOGY. J Exp Med. 1964 Mar 1;119:357–368. doi: 10.1084/jem.119.3.357. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. SHOPE R. E., WHITE D. C., LEIDY G. PORCINE CONTAGIOUS PLEUROPNEUMONIA. II. STUDIES OF THE PATHOGENICITY OF THE ETIOLOGICAL AGENT, HEMOPHILUS PLEUROPNEUMONIAE. J Exp Med. 1964 Mar 1;119:369–375. doi: 10.1084/jem.119.3.369. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Southern E. M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol. 1975 Nov 5;98(3):503–517. doi: 10.1016/s0022-2836(75)80083-0. [DOI] [PubMed] [Google Scholar]

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