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. 1984 Sep;45(3):781–783. doi: 10.1128/iai.45.3.781-783.1984

Interferon-gamma inhibits growth of Coxiella burnetii in mouse fibroblasts.

J Turco, H A Thompson, H H Winkler
PMCID: PMC263367  PMID: 6432701

Abstract

We studied the effects of various mouse interferon preparations on the growth of Coxiella burnetii in mouse fibroblasts. The addition of both recombinant interferon-gamma and a crude lymphokine preparation that contained interferon-gamma to infected L929 cells inhibited the growth of C. burnetii, whereas the addition of a crude preparation of type I interferons did not. Cycloheximide suppressed the inhibitory effects of recombinant interferon-gamma and crude lymphokines.

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Selected References

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