Table 1.

CNS phenotype of Wnt knockouts

Gene	CNS phenotype
Wnt1	Loss of midbrain, cerebellum,42,54 neural crest and dorsolateral neural precursors55
Wnt3	Regulation of hippocampal neurogenesis56
Wnt3a	Loss of hippocampus13
Wnt7a	Delayed synaptogenesis in cerebellum36
Lrp6	Reduction in neocortex during development30