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. 1984 Jun;44(3):750–752. doi: 10.1128/iai.44.3.750-752.1984

Phagocytosis, peritoneal influx, and enzyme activities in peritoneal macrophages from germfree, conventional, and ex-germfree mice.

B Mørland, T Midtvedt
PMCID: PMC263691  PMID: 6233226

Abstract

Peritoneal macrophages from germfree mice showed a higher basic activity of lysosomal enzymes than did macrophages from conventional mice, whereas oil-induced peritoneal influx, induction of lysosomal enzymes, and phagocytosis via the C3b receptor after endotoxin stimulation were reduced or absent. After germfree mice had been housed with conventional mice for 1 week, peritoneal influx and C3b receptor-mediated phagocytosis reached normal levels; after 4 weeks, enzyme activities also reached normal levels.

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Selected References

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