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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1994 May;32(5):1360–1361. doi: 10.1128/jcm.32.5.1360-1361.1994

Comparison of fecal lactoferrin latex agglutination assay and methylene blue microscopy for detection of fecal leukocytes in Clostridium difficile-associated disease.

W H Yong 1, A R Mattia 1, M J Ferraro 1
PMCID: PMC263702  PMID: 8051268

Abstract

The fecal lactoferrin assay was more sensitive (75%) than methylene blue microscopy (40%) for the detection of leukocytes in Clostridium difficile toxin-positive fecal samples. Although limited sensitivity and specificity precludes its use as a laboratory screening test, it may be a more useful initial test in an algorithm for clinically suspected C. difficile-associated disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bartlett J. G. Antibiotic-associated diarrhea. Clin Infect Dis. 1992 Oct;15(4):573–581. doi: 10.1093/clind/15.4.573. [DOI] [PubMed] [Google Scholar]
  2. Fekety R., Shah A. B. Diagnosis and treatment of Clostridium difficile colitis. JAMA. 1993 Jan 6;269(1):71–75. [PubMed] [Google Scholar]
  3. Guerrant R. L., Araujo V., Soares E., Kotloff K., Lima A. A., Cooper W. H., Lee A. G. Measurement of fecal lactoferrin as a marker of fecal leukocytes. J Clin Microbiol. 1992 May;30(5):1238–1242. doi: 10.1128/jcm.30.5.1238-1242.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Knoop F. C., Owens M., Crocker I. C. Clostridium difficile: clinical disease and diagnosis. Clin Microbiol Rev. 1993 Jul;6(3):251–265. doi: 10.1128/cmr.6.3.251. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Mattia A. R., Doern G. V., Clark J., Holden J., Wu L., Ferraro M. J. Comparison of four methods in the diagnosis of Clostridium difficile disease. Eur J Clin Microbiol Infect Dis. 1993 Nov;12(11):882–886. doi: 10.1007/BF02000416. [DOI] [PubMed] [Google Scholar]

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