Enhancement of L-type current density in IC neurons of SN-GEPR-3s. Ba2+ currents were activated at 0 mV in absence and presence of 10 μM nifedipine in IC neurons obtained from control SD rats and SN-GEPR-3s. A. Representative nifedipine-sensitive current trace (difference current in the presence and absence of nifedipine) in control SD rat (left trace) and SN-GEPR-3 (right trace).
B. Time course of the suppressive effect of nifedipine on HVA Ca2+ channel currents in control SD rat (left panel) and SN-GEPR-3 (right panel). C. Nifedipine-sensitive current (10 μM, L-type) was larger in SN-GEPR-3s (n = 8) compared to control SD rats (n = 10). **P <0.01.