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. 1994 Sep;32(9):2291–2294. doi: 10.1128/jcm.32.9.2291-2294.1994

Standardized microtiter assay for determination of syncytium-inducing phenotypes of clinical human immunodeficiency virus type 1 isolates.

A J Japour 1, S A Fiscus 1, J M Arduino 1, D L Mayers 1, P S Reichelderfer 1, D R Kuritzkes 1
PMCID: PMC263986  PMID: 7814561

Abstract

A standardized assay in 96-well microtiter plates for syncytium-inducing (SI) human immunodeficiency virus type 1 phenotype detection using MT-2 cells has been developed. SI variants were found in 67% of the patients with advanced human immunodeficiency virus disease. The occurrence of the SI phenotype increased with lower CD4+ counts. There was no association between p24 antigenemia and the SI phenotype.

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Selected References

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