Abstract
Persian Gulf War veterans have reported a variety of symptoms, many of which have not led to conventional diagnoses. We ascertained all active-duty U.S. military personnel deployed to the Persian Gulf War (552,111) and all Gulf War era military personnel not deployed (1,479,751) and compared their postwar hospitalization records (until 1 April 1996) for one or more of 77 diagnoses under the International Classification of Diseases (ICD-9) system. The diagnoses were assembled by the Emerging Infections Program, Centers for Disease Control and Prevention, and are here termed "unexplained illnesses." Deployed veterans were found to have a slightly higher risk of hospitalization for unexplained illness than the nondeployed. Most of the excess hospitalizations for the deployed were due to the diagnosis "illness of unknown cause" (ICD-9 code 799.9), and most occurred in participants of the Comprehensive Clinical Evaluation Program who were admitted for evaluation only. When the effect of participation in this program was removed, the deployed had a slightly lower risk than the nondeployed. These findings suggest that active-duty Gulf War veterans did not have excess unexplained illnesses resulting in hospitalization in the 4.67-year period following deployment.
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- Brodine S. K., Mascola J. R., Weiss P. J., Ito S. I., Porter K. R., Artenstein A. W., Garland F. C., McCutchan F. E., Burke D. S. Detection of diverse HIV-1 genetic subtypes in the USA. Lancet. 1995 Nov 4;346(8984):1198–1199. doi: 10.1016/s0140-6736(95)92901-0. [DOI] [PubMed] [Google Scholar]
- Cotton P. Gulf War symptoms remain puzzling. JAMA. 1992 Nov 18;268(19):2619–2619. [PubMed] [Google Scholar]
- Cowan D. N., DeFraites R. F., Gray G. C., Goldenbaum M. B., Wishik S. M. The risk of birth defects among children of Persian Gulf War veterans. N Engl J Med. 1997 Jun 5;336(23):1650–1656. doi: 10.1056/NEJM199706053362306. [DOI] [PubMed] [Google Scholar]
- Gray G. C., Coate B. D., Anderson C. M., Kang H. K., Berg S. W., Wignall F. S., Knoke J. D., Barrett-Connor E. The postwar hospitalization experience of U.S. veterans of the Persian Gulf War. N Engl J Med. 1996 Nov 14;335(20):1505–1513. doi: 10.1056/NEJM199611143352007. [DOI] [PubMed] [Google Scholar]
- Kang H. K., Bullman T. A. Mortality among U.S. veterans of the Persian Gulf War. N Engl J Med. 1996 Nov 14;335(20):1498–1504. doi: 10.1056/NEJM199611143352006. [DOI] [PubMed] [Google Scholar]
- Magill A. J., Grögl M., Gasser R. A., Jr, Sun W., Oster C. N. Visceral infection caused by Leishmania tropica in veterans of Operation Desert Storm. N Engl J Med. 1993 May 13;328(19):1383–1387. doi: 10.1056/NEJM199305133281904. [DOI] [PubMed] [Google Scholar]
- Maurice J. Russian chaos breeds diphtheria outbreak. Science. 1995 Mar 10;267(5203):1416–1417. doi: 10.1126/science.7878458. [DOI] [PubMed] [Google Scholar]
- Nicolson G. L., Rosenberg-Nicolson N. L. Doxycycline treatment and Desert Storm. JAMA. 1995 Feb 22;273(8):618–619. doi: 10.1001/jama.273.8.618. [DOI] [PubMed] [Google Scholar]
- Perkins B. A., Flood J. M., Danila R., Holman R. C., Reingold A. L., Klug L. A., Virata M., Cieslak P. R., Zaki S. R., Pinner R. W. Unexplained deaths due to possibly infectious causes in the United States: defining the problem and designing surveillance and laboratory approaches. The Unexplained Deaths Working Group. Emerg Infect Dis. 1996 Jan-Mar;2(1):47–53. doi: 10.3201/eid0201.960106. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wallace M. R., Sharp T. W., Romajzl P. J., Batchelor R. A., Thornton S. A., Longer C. F., Burans J. P. Malaria in Mogadishu, Somalia. Clin Infect Dis. 1993 Sep;17(3):510–511. doi: 10.1093/clinids/17.3.510. [DOI] [PubMed] [Google Scholar]
- Writer J. V., DeFraites R. F., Brundage J. F. Comparative mortality among US military personnel in the Persian Gulf region and worldwide during Operations Desert Shield and Desert Storm. JAMA. 1996 Jan 10;275(2):118–121. [PubMed] [Google Scholar]
