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. 1998 Jul-Sep;4(3):398–403. doi: 10.3201/eid0403.980313

Malaria: a reemerging disease in Africa.

T C Nchinda 1
PMCID: PMC2640295  PMID: 9716954

Abstract

A recent upsurge of malaria in endemic-disease areas with explosive epidemics in many parts of Africa is probably caused by many factors, including rapidly spreading resistance to antimalarial drugs, climatic changes, and population movements. In Africa, malaria is caused by Plasmodium falciparum and is transmitted by Anopheles gambiae complex. Control efforts have been piecemeal and not coordinated. Strategies for control should have a solid research base both for developing antimalarial drugs and vaccines and for better understanding the pathogenesis, vector dynamics, epidemiology, and socioeconomic aspects of the disease. An international collaborative approach is needed to build appropriate research in a national context and to effectively translate research results into practical applications in the field. The Multilateral Initiative for Malaria in Africa can combine all of the above strategies to plan and coordinate partnerships, networking, and innovative approaches between African scientists and their Northern partners.

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Selected References

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  1. Alonso P. L., Lindsay S. W., Armstrong J. R., Conteh M., Hill A. G., David P. H., Fegan G., de Francisco A., Hall A. J., Shenton F. C. The effect of insecticide-treated bed nets on mortality of Gambian children. Lancet. 1991 Jun 22;337(8756):1499–1502. doi: 10.1016/0140-6736(91)93194-e. [DOI] [PubMed] [Google Scholar]
  2. Binka F. N., Kubaje A., Adjuik M., Williams L. A., Lengeler C., Maude G. H., Armah G. E., Kajihara B., Adiamah J. H., Smith P. G. Impact of permethrin impregnated bednets on child mortality in Kassena-Nankana district, Ghana: a randomized controlled trial. Trop Med Int Health. 1996 Apr;1(2):147–154. doi: 10.1111/j.1365-3156.1996.tb00020.x. [DOI] [PubMed] [Google Scholar]
  3. Carlson J., Olson K., Higgs S., Beaty B. Molecular genetic manipulation of mosquito vectors. Annu Rev Entomol. 1995;40:359–388. doi: 10.1146/annurev.en.40.010195.002043. [DOI] [PubMed] [Google Scholar]
  4. Mons B., Klasen E., van Kessel R., Nchinda T. Partnership between south and north crystallizes around malaria. Science. 1998 Jan 23;279(5350):498–499. doi: 10.1126/science.279.5350.498. [DOI] [PubMed] [Google Scholar]
  5. Nevill C. G., Some E. S., Mung'ala V. O., Mutemi W., New L., Marsh K., Lengeler C., Snow R. W. Insecticide-treated bednets reduce mortality and severe morbidity from malaria among children on the Kenyan coast. Trop Med Int Health. 1996 Apr;1(2):139–146. doi: 10.1111/j.1365-3156.1996.tb00019.x. [DOI] [PubMed] [Google Scholar]
  6. Pagnoni F., Convelbo N., Tiendrebeogo J., Cousens S., Esposito F. A community-based programme to provide prompt and adequate treatment of presumptive malaria in children. Trans R Soc Trop Med Hyg. 1997 Sep-Oct;91(5):512–517. doi: 10.1016/s0035-9203(97)90006-7. [DOI] [PubMed] [Google Scholar]
  7. Snow R. W., Schellenberg J. R., Peshu N., Forster D., Newton C. R., Winstanley P. A., Mwangi I., Waruiru C., Warn P. A., Newbold C. Periodicity and space-time clustering of severe childhood malaria on the coast of Kenya. Trans R Soc Trop Med Hyg. 1993 Jul-Aug;87(4):386–390. doi: 10.1016/0035-9203(93)90007-d. [DOI] [PubMed] [Google Scholar]

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