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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1994 Jun;32(6):1604–1605. doi: 10.1128/jcm.32.6.1604-1605.1994

Evidence of pestivirus RNA in human virus vaccines.

R Harasawa 1, T Tomiyama 1
PMCID: PMC264050  PMID: 8077414

Abstract

We examined live virus vaccines against measles, mumps, and rubella for the presence of pestivirus RNA or of pestiviruses by reverse transcription PCR. Pestivirus RNA was detected in two measles-mumps-rubella combined vaccines and in two monovalent vaccines against mumps and rubella. Nucleotide sequence analysis of the PCR products indicated that a modified live vaccine strain used for immunization of cattle against bovine viral diarrhea is not responsible for the contamination of the vaccines.

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Selected References

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