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Journal of the National Medical Association logoLink to Journal of the National Medical Association
. 2000 Feb;92(2):83–86.

Lactobacillemia: an emerging cause of infection in both the immunocompromised and the immunocompetent host.

S J Antony 1
PMCID: PMC2640534  PMID: 10800296

Abstract

The bacterium, lactobacillus, is found in the mucosal surfaces of the mouth and the gastrointestinal and genitourinary tracts. There have been increasing reports of the micro-organism being a cause of serious infection in immunocompromised individuals. This article reviews the clinical presentation, laboratory characteristics and treatment of patients with lactobacillemia.

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Selected References

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  1. Abgrall S., Joly V., Derkinderen P., Decré D., Carbon C., Yeni P. Lactobacillus casei infection in an AIDS patient. Eur J Clin Microbiol Infect Dis. 1997 Feb;16(2):180–182. doi: 10.1007/BF01709485. [DOI] [PubMed] [Google Scholar]
  2. Andriessen M. P., Mulder J. G., Sleijfer D. T. Lactobacillus septicemia, an unusual complication during the treatment of metastatic choriocarcinoma. Gynecol Oncol. 1991 Jan;40(1):87–89. doi: 10.1016/0090-8258(91)90093-k. [DOI] [PubMed] [Google Scholar]
  3. Antony S. J., Stratton C. W., Dummer J. S. Lactobacillus bacteremia: description of the clinical course in adult patients without endocarditis. Clin Infect Dis. 1996 Oct;23(4):773–778. doi: 10.1093/clinids/23.4.773. [DOI] [PubMed] [Google Scholar]
  4. Bayer A. S., Chow A. W., Betts D., Guze L. B. Lactobacillemia--report of nine cases. Important clinical and therapeutic considerations. Am J Med. 1978 May;64(5):808–813. doi: 10.1016/0002-9343(78)90521-1. [DOI] [PubMed] [Google Scholar]
  5. Bourne K. A., Beebe J. L., Lue Y. A., Ellner P. D. Bacteremia due to Bifidobacterium, Eubacterium or Lactobacillus; twenty-one cases and review of the literature. Yale J Biol Med. 1978 Sep-Oct;51(5):505–512. [PMC free article] [PubMed] [Google Scholar]
  6. Buchner L. H., Schneierson S. Clinical and laboratory aspects of Listeria monocytogenes infections. With a report of ten cases. Am J Med. 1968 Dec;45(6):904–921. doi: 10.1016/0002-9343(68)90189-7. [DOI] [PubMed] [Google Scholar]
  7. Chomarat M., Espinouse D. Lactobacillus rhamnosus septicemia in patients with prolonged aplasia receiving ceftazidime-vancomycin. Eur J Clin Microbiol Infect Dis. 1991 Jan;10(1):44–44. doi: 10.1007/BF01967099. [DOI] [PubMed] [Google Scholar]
  8. Cooper C. D., Vincent A., Greene J. N., Sandin R. L., Cobian L. Lactobacillus bacteremia in febrile neutropenic patients in a cancer hospital. Clin Infect Dis. 1998 May;26(5):1247–1248. doi: 10.1086/598365. [DOI] [PubMed] [Google Scholar]
  9. Fruchart C., Salah A., Gray C., Martin E., Stamatoullas A., Bonmarchand G., Lemeland J. F., Tilly H. Lactobacillus species as emerging pathogens in neutropenic patients. Eur J Clin Microbiol Infect Dis. 1997 Sep;16(9):681–684. doi: 10.1007/BF01708560. [DOI] [PubMed] [Google Scholar]
  10. Griffiths J. K., Daly J. S., Dodge R. A. Two cases of endocarditis due to Lactobacillus species: antimicrobial susceptibility, review, and discussion of therapy. Clin Infect Dis. 1992 Aug;15(2):250–255. doi: 10.1093/clinids/15.2.250. [DOI] [PubMed] [Google Scholar]
  11. Holliman R. E., Bone G. P. Vancomycin resistance of clinical isolates of lactobacilli. J Infect. 1988 May;16(3):279–283. doi: 10.1016/s0163-4453(88)97676-1. [DOI] [PubMed] [Google Scholar]
  12. Horwitch C. A., Furseth H. A., Larson A. M., Jones T. L., Olliffe J. F., Spach D. H. Lactobacillemia in three patients with AIDS. Clin Infect Dis. 1995 Dec;21(6):1460–1462. doi: 10.1093/clinids/21.6.1460. [DOI] [PubMed] [Google Scholar]
  13. Husni R. N., Gordon S. M., Washington J. A., Longworth D. L. Lactobacillus bacteremia and endocarditis: review of 45 cases. Clin Infect Dis. 1997 Nov;25(5):1048–1055. doi: 10.1086/516109. [DOI] [PubMed] [Google Scholar]
  14. Manzella J. P., Harootunian R. Lactobacillemia of renal origin: a case report. J Urol. 1982 Jul;128(1):110–110. doi: 10.1016/s0022-5347(17)52776-7. [DOI] [PubMed] [Google Scholar]
  15. Patel R., Cockerill F. R., Porayko M. K., Osmon D. R., Ilstrup D. M., Keating M. R. Lactobacillemia in liver transplant patients. Clin Infect Dis. 1994 Feb;18(2):207–212. doi: 10.1093/clinids/18.2.207. [DOI] [PubMed] [Google Scholar]
  16. Sacks P. C., Tchabo J. G. Incidence of bacteremia at dilation and curettage. J Reprod Med. 1992 Apr;37(4):331–334. [PubMed] [Google Scholar]
  17. Schoon Y., Schuurman B., Buiting A. G., Kranendonk S. E., Graafsma S. J. Aortic graft infection by Lactobacillus casei: a case report. Neth J Med. 1998 Feb;52(2):71–74. doi: 10.1016/s0300-2977(97)00079-x. [DOI] [PubMed] [Google Scholar]
  18. Sherman M. E., Albrecht M., DeGirolami P. C., Kirkley S. A., Wolf B., Eliopoulos G. M., Rohrer R. J., Monaco A. P. An unusual case of splenic abscess and sepsis in an immunocompromised host. Am J Clin Pathol. 1987 Nov;88(5):659–662. doi: 10.1093/ajcp/88.5.659. [DOI] [PubMed] [Google Scholar]
  19. Sussman J. I., Baron E. J., Goldberg S. M., Kaplan M. H., Pizzarello R. A. Clinical manifestations and therapy of Lactobacillus endocarditis: report of a case and review of the literature. Rev Infect Dis. 1986 Sep-Oct;8(5):771–776. doi: 10.1093/clinids/8.5.771. [DOI] [PubMed] [Google Scholar]
  20. Swenson J. M., Facklam R. R., Thornsberry C. Antimicrobial susceptibility of vancomycin-resistant Leuconostoc, Pediococcus, and Lactobacillus species. Antimicrob Agents Chemother. 1990 Apr;34(4):543–549. doi: 10.1128/aac.34.4.543. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Weinstein M. P., Reller L. B., Murphy J. R., Lichtenstein K. A. The clinical significance of positive blood cultures: a comprehensive analysis of 500 episodes of bacteremia and fungemia in adults. I. Laboratory and epidemiologic observations. Rev Infect Dis. 1983 Jan-Feb;5(1):35–53. doi: 10.1093/clinids/5.1.35. [DOI] [PubMed] [Google Scholar]

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