Abstract
Hypersensitivity pneumonitis (HP) in workers exposed to metal removal fluids (MRFs) is increasing. This study supports the hypothesis that aerosolized mycobacteria colonizing the MRFs likely cause the disease. Three case studies of HP outbreaks among metal workers showed potentially high exposures to a rare and newly proposed Mycobacterium species. Retrospective review of samples submitted to our laboratory showed an association between presence of mycobacteria and HP.
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Selected References
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- Bernstein D. I., Lummus Z. L., Santilli G., Siskosky J., Bernstein I. L. Machine operator's lung. A hypersensitivity pneumonitis disorder associated with exposure to metalworking fluid aerosols. Chest. 1995 Sep;108(3):636–641. doi: 10.1378/chest.108.3.636. [DOI] [PubMed] [Google Scholar]
- Centers for Disease Control and Prevention (CDC) Biopsy-confirmed hypersensitivity pneumonitis in automobile production workers exposed to metalworking fluids--Michigan, 1994-1995. MMWR Morb Mortal Wkly Rep. 1996 Jul 19;45(28):606–610. [PubMed] [Google Scholar]
- Embil J., Warren P., Yakrus M., Stark R., Corne S., Forrest D., Hershfield E. Pulmonary illness associated with exposure to Mycobacterium-avium complex in hot tub water. Hypersensitivity pneumonitis or infection? Chest. 1997 Mar;111(3):813–816. doi: 10.1378/chest.111.3.813. [DOI] [PubMed] [Google Scholar]
- Kreiss K., Cox-Ganser J. Metalworking fluid-associated hypersensitivity pneumonitis: a workshop summary. Am J Ind Med. 1997 Oct;32(4):423–432. doi: 10.1002/(sici)1097-0274(199710)32:4<423::aid-ajim16>3.0.co;2-5. [DOI] [PubMed] [Google Scholar]
- Zacharisen M. C., Kadambi A. R., Schlueter D. P., Kurup V. P., Shack J. B., Fox J. L., Anderson H. A., Fink J. N. The spectrum of respiratory disease associated with exposure to metal working fluids. J Occup Environ Med. 1998 Jul;40(7):640–647. doi: 10.1097/00043764-199807000-00010. [DOI] [PubMed] [Google Scholar]