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. 2000 Mar-Apr;6(2):184–187. doi: 10.3201/eid0602.000213

Sin nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome.

P Bostik 1, J Winter 1, T G Ksiazek 1, P E Rollin 1, F Villinger 1, S R Zaki 1, C J Peters 1, A A Ansari 1
PMCID: PMC2640842  PMID: 10756154

Abstract

Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100% and 67% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%).

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Selected References

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