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. 2000 Mar-Apr;6(2):180–183. doi: 10.3201/eid0602.000212

Erythromycin resistance in Streptococcus pyogenes in Italy.

M Bassetti 1, G Manno 1, A Collidà 1, A Ferrando 1, G Gatti 1, E Ugolotti 1, M Cruciani 1, D Bassetti 1
PMCID: PMC2640849  PMID: 10756153

Abstract

In a prospective study of acute pharyngitis in Italian children, 69 (38.3%) of 180 isolates of Streptococcus pyogenes were resistant to macrolides. S. pyogenes was eradicated in 12 (63.1%) of 19 patients with erythromycin-resistant S. pyogenes treated with clarithromycin and in 22 (88%) of 25 patients with erythromycin-susceptible strains. The constitutive-resistant phenotype was correlated with failure of macrolide treatment.

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Selected References

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