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. 2000 Nov-Dec;6(6):616–621. doi: 10.3201/eid0606.000610

Hantavirus pulmonary syndrome associated with Monongahela virus, Pennsylvania.

L V Rhodes 3rd 1, C Huang 1, A J Sanchez 1, S T Nichol 1, S R Zaki 1, T G Ksiazek 1, J G Humphreys 1, J J Freeman 1, K R Knecht 1
PMCID: PMC2640920  PMID: 11076720

Abstract

The first two recognized cases of rapidly fatal hantavirus pulmonary syndrome in Pennsylvania occurred within an 8-month period in 1997. Illness in the two patients was confirmed by immunohistochemical techniques on autopsy material. Reverse transcription-polymerase chain reaction analysis of tissue from one patient and environmentally associated Peromyscus leucopus (white-footed mouse) identified the Monongahela virus variant. Physicians should be vigilant for such Monongahela virus-associated cases in the eastern United States and Canada, particularly in the Appalachian region.

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Selected References

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