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. 1994 Oct;32(10):2572–2575. doi: 10.1128/jcm.32.10.2572-2575.1994

Pneumococcal resistance to antimicrobial agents in the province of Québec, Canada.

L P Jetté 1, L Ringuette 1, A Dascal 1, J R Lapointe 1, P Turgeon 1
PMCID: PMC264105  PMID: 7814501

Abstract

The serogroup/serotypes (SGTs) and antimicrobial susceptibilities to 10 antimicrobial agents of 110 clinical strains of Streptococcus pneumoniae were determined. Strains intermediately resistant or highly resistant to penicillin G (80 of 110) belonged predominantly to SGTs 23 (45.0%), 19 (13.7%), 6 (10.0%), 9 (6.2%), and 14 (3.7%). The MICs of all cephalosporins, tetracycline, trimethoprim-sulfamethoxazole, and chloramphenicol increased along with the MICs of penicillin G. However, erythromycin resistance and clindamycin resistance were observed more frequently among the intermediately penicillin-resistant strains. Multiple resistance was observed for 32 strains, of which 25 were highly resistant to penicillin G and belong to SGT 23F. All strains were susceptible to vancomycin.

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Selected References

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