Table 1.
Patient | Isolate | Virus phenotype* | CD4 count† | AIDS onset, mo‡ | Death, mo‡ |
---|---|---|---|---|---|
A | J2195 | NSI | 600 | +55 | +71 |
J4052 | SI | 260 | +35 | +52 | |
B | J562 | NSI | 250 | +4 | +25 |
J975 | SI | 110 | −4 | +17 | |
C | J669 | NSI | 320 | +11 | +66 |
J1629 | SI | 210 | −4 | +51 | |
D | J1874 | NSI | 360 | —§ | —§ |
J2337 | SI | 410 | —§ | —§ | |
E | J2090 | NSI | 50 | +10 | +31 |
J2822 | SI | 20 | +4 | +25 | |
F | J2234 | NSI | 310 | +24 | +43 |
J4996 | NSI | 190 | −3 | +16 | |
G | J1228 | NSI | 320 | +9 | +41 |
J4482 | NSI | 5 | −26 | +6 | |
H | J624 | NSI | 290 | +27 | +42 |
J3899 | NSI | 6¶ | −14 | +1 |
Virus isolates obtained sequentially with (i) switched phenotype from NSI to SI (patients A–E) and (ii) maintained NSI phenotype despite AIDS (patients F–H). Absolute counts of CD4+ lymphocytes were measured at time of virus isolation, and time span to onset of AIDS or death was calculated in relation to the time of virus isolation.
Virus phenotype as classified by MT-2 assay.
CD4+ lymphocyte count in cells/mm3.
Time span in months to the onset of AIDS or to death in relation to the time of the virus isolation; − before isolation; +, after isolation.
Patient D had not developed AIDS and was alive at time of collection of clinical data.
Available CD4 count was measured 6 months before virus isolation.