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. 1984 Mar;43(3):800–803. doi: 10.1128/iai.43.3.800-803.1984

Monoclonal antibodies to immunodeterminants of lipoteichoic acids.

D E Jackson, W Wong, M T Largen, G D Shockman
PMCID: PMC264251  PMID: 6199301

Abstract

Murine hybrid cell lines producing monoclonal antibodies directed against determinants present on lipoteichoic acids were generated. Hapten inhibition studies showed that one group of monoclonal antibodies was inhibited by deacylated cardiolipin, and the second group was inhibited by kojibiose. Thus, antibodies directed against the polyglycerophosphate chain, which is common to the lipoteichoic acids of many gram-positive species, and against the streptococcal group D antigen were obtained.

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Selected References

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  1. Cornett J. B., Redman B. E., Shockman G. D. Autolytic defective mutant of Streptococcus faecalis. J Bacteriol. 1978 Feb;133(2):631–640. doi: 10.1128/jb.133.2.631-640.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Hewett M. J., Knox K. W., Wicken A. J. Studies on the group F antigen of lactobacilli: detection of antibodies by haemagglutination. J Gen Microbiol. 1970 Mar;60(3):315–322. doi: 10.1099/00221287-60-3-315. [DOI] [PubMed] [Google Scholar]
  3. Jackson D. E., Jackson G. D., Wicken A. J. Induction of IgM immunological memory to lipoteichoic acids in rabbits. Part I. Int Arch Allergy Appl Immunol. 1981;65(2):198–202. doi: 10.1159/000232756. [DOI] [PubMed] [Google Scholar]
  4. Jacques N. A., Hardy L., Campbell L. K., Knox K. W., Evans J. D., Wicken A. J. Effect of carbohydrate source and growth conditions on the production of lipoteichoic acid by Streptococcus mutans Ingbritt. Infect Immun. 1979 Dec;26(3):1079–1087. doi: 10.1128/iai.26.3.1079-1087.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Kessler R. E., Thivierge B. H. Effects of substitution on polyglycerol phosphate-specific antibody binding to lipoteichoic acids. Infect Immun. 1983 Aug;41(2):549–555. doi: 10.1128/iai.41.2.549-555.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Knox K. W., Wicken A. J. Immunological properties of teichoic acids. Bacteriol Rev. 1973 Jun;37(2):215–257. doi: 10.1128/br.37.2.215-257.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Nealon T. J., Mattingly S. J. Association of elevated levels of cellular lipoteichoic acids of group B streptococci with human neonatal disease. Infect Immun. 1983 Mar;39(3):1243–1251. doi: 10.1128/iai.39.3.1243-1251.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Shulman M., Wilde C. D., Köhler G. A better cell line for making hybridomas secreting specific antibodies. Nature. 1978 Nov 16;276(5685):269–270. doi: 10.1038/276269a0. [DOI] [PubMed] [Google Scholar]
  9. Silvestri L. J., Craig R. A., Ingram L. O., Hoffmann E. M., Bleiweis A. S. Purification of lipoteichoic acids by using phosphatidyl choline vesicles. Infect Immun. 1978 Oct;22(1):107–118. doi: 10.1128/iai.22.1.107-118.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. WICKEN A. J., BADDILEY J. Structure of intracellular teichoic acids from group D streptococci. Biochem J. 1963 Apr;87:54–62. doi: 10.1042/bj0870054. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. WICKEN A. J., ELLIOTT S. D., BADDILEY J. The identity of streptococcal group D antigen with teichoic acid. J Gen Microbiol. 1963 May;31:231–239. doi: 10.1099/00221287-31-2-231. [DOI] [PubMed] [Google Scholar]
  12. Wicken A. J., Gibbens J. W., Knox K. W. Comparative studies on the isolation of membrane lipoteichoic acid from Lactobacillus fermenti. J Bacteriol. 1973 Jan;113(1):365–372. doi: 10.1128/jb.113.1.365-372.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Wicken A. J., Knox K. W. Bacterial cell surface amphiphiles. Biochim Biophys Acta. 1980 May 27;604(1):1–26. doi: 10.1016/0005-2736(80)90583-0. [DOI] [PubMed] [Google Scholar]
  14. Wicken A. J., Knox K. W. Studies on the group F antigen of lactobacilli: isolation of a teichoic acid-lipid complex from Lactobacillus fermenti NCTC 6991. J Gen Microbiol. 1970 Mar;60(3):293–301. doi: 10.1099/00221287-60-3-293. [DOI] [PubMed] [Google Scholar]

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