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. 1984 Mar;43(3):876–878. doi: 10.1128/iai.43.3.876-878.1984

Phosphorylcholine determinants in six pneumococcal capsular polysaccharides detected by monoclonal antibody.

U B Sørensen, R Agger, J Bennedsen, J Henrichsen
PMCID: PMC264264  PMID: 6199306

Abstract

The presence of phosphorylcholine in pneumococcal capsular polysaccharides was examined by using monoclonal antiphosphorylcholine antibody. Of the 83 known capsular types of Streptococcus pneumoniae, 6 types, viz., 24A, 27, 28F, 28A, 32F, and 32A, gave a positive capsular reaction (quellung) which could be inhibited by phosphorylcholine. The capsular polysaccharides of these six types, therefore, contain phosphorylcholine.

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Selected References

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