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. 1984 Feb;43(2):775–778. doi: 10.1128/iai.43.2.775-778.1984

Chemotactic and phagocytic responses of human alveolar macrophages to activated complement components.

S W Richards, P K Peterson, H A Verbrugh, R D Nelson, D E Hammerschmidt, J R Hoidal
PMCID: PMC264372  PMID: 6693176

Abstract

Human alveolar macrophages (AMs) migrated toward and aggregated to C5a but not toward C5a-deficient serum. Human AMs from cigarette smokers migrated significantly farther than did AMs from nonsmokers. Human AMs phagocytized Escherichia coli opsonized with activated C3. Immunoglobulin G was not required for phagocytosis. Human AMs demonstrate chemotaxis and aggregation to C5a. Further, human AMs can phagocytize bacteria coated with activated C3.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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