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The Canadian Journal of Cardiology logoLink to The Canadian Journal of Cardiology
letter
. 2008 Nov;24(11):832–844.

Incomplete revascularization in beating heart surgery

Camille L Hancock Friesen 1, John A Sullivan 1
PMCID: PMC2644532  PMID: 19004074

To the Editor:

We would like to congratulate Dr Ivanov and co-authors on their retrospective review of mid-term outcomes of beating heart surgery (BHS) versus conventional on-pump coronary artery bypass (CCAB) graft surgery. Fewer coronary artery bypass grafts performed in the BHS cohort were correlated with a reduced interval of freedom from cardiac events or cardiac reintervention compared with the CCAB cohort. The finding that there are fewer bypass grafts performed in BHS cases than in CCAB cases, despite being matched for disease burden, is in complete concordance with our report (1) of 400 cases of propensity-matched BHS and CCAB. This was the first report in the literature to show that a BHS cohort had lower rates of complete revascularization than CCAB patients.

In a study of BHS and CCAB procedures (1) performed from 1997 through 2002, angiograms were reviewed and scored for vessel disease and graftability, and BHS and CCAB cases were matched for comorbidities and number of graftable vessels. We found that the BHS group received, on average, significantly fewer grafts than the CCAB group (2.4±1.0 versus 3.2±1.0; P<0.0001). The greater the disease burden, the less likely the BHS group was to be completely revascularized. Patients with fewer than three diseased vessels grafted using the BHS technique were significantly less likely to be completely revascularized than CCAB patients (78% versus 94%; P=0.036). In patients with three graftable vessels, complete revascularization was achieved in 51.2% of the BHS patients versus 80% of the CCAB patients (P=0.0003), and in patients with more than three graftable vessels, the rates of complete revascularization in BHS versus CCAB patients were 17.6% and 51%, respectively (P=0.0012). The graft distribution was significantly different between the BHS and CCAB groups (Table 1).

Table 1.

Technical graft details

CCABG OPCABG P
Distal anastomoses, n 631 470
Bypass number, n (%)
  Single 8 (4) 43 (22)
  Double 40 (20) 68 (34)
  Triple 89 (45) 69 (35)
  Quadruple 43 (22) 17 (9)
  Quintuple 16 (8) 2 (1)
Graft conduit, n (%)
  Saphenous vein graft 98 (49) 72 (36) 0.0085
  Left internal mammary artery 170 (85) 184 (92) 0.28
  Right internal mammary artery 66 (33) 79 (40) 0.18
  Bilateral internal mammary artery 60 (30) 68 (34) 0.39
  Radial artery 74 (37) 28 (14) <0.001
Graft distribution, n (%)
  Left anterior descending artery 167 (84) 184 (92) 0.0095
  Diagonal artery 78 (39) 56 (28)
  RCA, AM, PLV, PDA 184 (92) 114 (57)
  Circumflex artery, RI, OM 198 (99) 114 (57)
Total arterial grafts, n (%) 103 (52) 129 (65) 0.0084

AM Acute marginal artery; CCABG Conventional coronary artery bypass grafting; OM Obtuse marginal artery; OPCABG Off-pump coronary artery bypass grafting; PDA Posterior descending artery; PLV Posterior left ventricular artery; RCA Right coronary artery; RI Ramus intermedius artery. Data from reference 1

With previous evidence of incomplete revascularization in BHS patients (1), and the negative impact of incomplete revascularization on both early and late mortality rates and freedom from recurrent cardiac events (2,3), the finding by Dr Ivanov and colleagues is not surprising, but it is a very important contribution to the literature and provides a more complete picture of off-pump coronary artery bypass grafting and where it should fit in our surgical armamentarium.

REFERENCES

  • 1.Hancock Friesen C, Buth K, Thompson G, Sullivan J, Hirsch G. Does beating heart surgery compromise complete vascularization? Cardiovascular Engineering. 2000;5:110. [Google Scholar]
  • 2.Bell MR, Gersh BJ, Schaff HV, et al. Effect of completeness of revascularization on long-term outcome of patients with three-vessel disease undergoing coronary artery bypass surgery. A report from the Coronary Artery Surgery Study (CASS) Registry. Circulation. 1992;86:446–57. doi: 10.1161/01.cir.86.2.446. [DOI] [PubMed] [Google Scholar]
  • 3.Osswald BR, Blackstone EH, Tochtermann U, et al. Does the completeness of revascularization affect early survival after coronary artery bypass grafting in elderly patients? Eur J Cardiothorac Surg. 2001;20:120–5. doi: 10.1016/s1010-7940(01)00743-6. [DOI] [PubMed] [Google Scholar]

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