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. 1983 Nov;42(2):579–584. doi: 10.1128/iai.42.2.579-584.1983

Isolation and preliminary characterization of circulating immune complexes from rabbits with experimental syphilis.

R E Baughn, D M Musher
PMCID: PMC264467  PMID: 6358025

Abstract

Immune complexes isolated from sera of rabbits with experimental, disseminated syphilis were found to have sedimentation coefficients greater than 19s. By radioimmunoblot assays, materials precipitated with 2.5% polyethylene glycol or chromatographed on DEAE-Affi-Gel Blue were found to contain albumin, C3, immunoglobulin M (IgM), IgG, and treponemal antigen(s), whereas control materials contained only albumin and IgG. When polyethylene glycol precipitation of immune complexes from syphilitic rabbits was followed by immobilization on protein A and acid elution, radioimmunoblots detected only IgG and treponemal antigen(s).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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