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. 1983 Nov;42(2):623–627. doi: 10.1128/iai.42.2.623-627.1983

Comparison of major protein antigens and protein profiles of Treponema pallidum and Treponema pertenue.

R W Thornburg, J B Baseman
PMCID: PMC264474  PMID: 6358027

Abstract

The protein profiles of Treponema pallidum and Treponema pertenue, the causative agents of syphilis and yaws, respectively, were compared by one- and two-dimensional gel electrophoresis. One-dimensional gels showed essentially no differences in the protein patterns of these treponemes. On two-dimensional gels most radiolabeled protein species were shared; however, variations were noticed in several minor protein species. Antigenic comparison by radioimmunoprecipitation and Western blotting also demonstrated similarities between these spirochetes. However, lactoperoxidase-catalyzed iodination of T. pallidum and T. pertenue suggested differences in their surface proteins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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