Skip to main content
Infection and Immunity logoLink to Infection and Immunity
. 1983 Oct;42(1):418–420. doi: 10.1128/iai.42.1.418-420.1983

Antigenic relatedness of two strains of hepatitis A virus determined by cross-neutralization.

S M Lemon, L N Binn
PMCID: PMC264574  PMID: 6194118

Abstract

Cell culture-adapted HM-175 (Australia) and PA-21 (Panama) strains of hepatitis A virus were compared in a cross-neutralization radioimmunofocus inhibition assay. The ratio of antibody titers achieved with two sera against the two viruses differed by less than twofold, indicating a high degree of antigenic relatedness between epidemiologically disparate strains of virus.

Full text

PDF
418

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Daemer R. J., Feinstone S. M., Gust I. D., Purcell R. H. Propagation of human hepatitis A virus in African green monkey kidney cell culture: primary isolation and serial passage. Infect Immun. 1981 Apr;32(1):388–393. doi: 10.1128/iai.32.1.388-393.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. LeDuc J. W., Lemon S. M., Keenan C. M., Graham R. R., Marchwicki R. H., Binn L. N. Experimental infection of the New World owl monkey (Aotus trivirgatus) with hepatitis A virus. Infect Immun. 1983 May;40(2):766–772. doi: 10.1128/iai.40.2.766-772.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Lemon S. M., Binn L. N., Marchwicki R. H. Radioimmunofocus assay for quantitation of hepatitis A virus in cell cultures. J Clin Microbiol. 1983 May;17(5):834–839. doi: 10.1128/jcm.17.5.834-839.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Lemon S. M., LeDuc J. W., Binn L. N., Escajadillo A., Ishak K. G. Transmission of hepatitis A virus among recently captured Panamanian owl monkeys. J Med Virol. 1982;10(1):25–36. doi: 10.1002/jmv.1890100105. [DOI] [PubMed] [Google Scholar]
  5. Provost P. J., Ittensohn O. L., Villarejos V. M., Arguedas J. A., Hilleman M. R. Etiologic relationship of marmoset-propagated CR326 hepatitis A virus to hepatitis in man. Proc Soc Exp Biol Med. 1973 Apr;142(4):1257–1267. doi: 10.3181/00379727-142-37220. [DOI] [PubMed] [Google Scholar]
  6. Rakela J., Fay O. H., Stevenson D., Gordon I., Mosley J. W. Similarities of two hepatitis A virus strains. Bull World Health Organ. 1976;54(5):561–564. [PMC free article] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES