Abstract
The microbicidal activity of an acetate extract of human polymorphonuclear leukocyte granules was tested against Bacteroides fragilis, Bacteroides vulgatus, Bacteroides distasonis and Bacteroides thetaiotaomicron. All strains tested were killed by the extract, and there were no significant differences between the different Bacteroides species.
Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Babb J. L., Cummins C. S. Encapsulation of Bacteroides species. Infect Immun. 1978 Mar;19(3):1088–1091. doi: 10.1128/iai.19.3.1088-1091.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Babior B. M. Oxygen-dependent microbial killing by phagocytes (second of two parts). N Engl J Med. 1978 Mar 30;298(13):721–725. doi: 10.1056/NEJM197803302981305. [DOI] [PubMed] [Google Scholar]
- Bjornson A. B., Altemeier W. A., Bjornson H. S. Comparison of the in vitro bactericidal activity of human serum and leukocytes against bacteroides fragilis and Fusobacterium mortiferum in aerobic and anaerobic environments. Infect Immun. 1976 Sep;14(3):843–847. doi: 10.1128/iai.14.3.843-847.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DeChatelet L. R. Initiation of the respiratory burst in human polymorphonuclear neutrophils: a critical review. J Reticuloendothel Soc. 1978 Jul;24(1):73–91. [PubMed] [Google Scholar]
- Friedberg D., Shilo M. Interaction of Gram-Negative Bacteria with the Lysosomal Fraction of Polymorphonuclear Leukocytes I. Role of Cell Wall Composition of Salmonella typhimurium. Infect Immun. 1970 Mar;1(3):305–310. doi: 10.1128/iai.1.3.305-310.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ingham H. R., Sisson P. R., Middleton R. L., Narang H. K., Codd A. A., Selkon J. B. Phagocytosis and killing of bacteria in aerobic and anaerobic conditions. J Med Microbiol. 1981 Nov;14(4):391–399. doi: 10.1099/00222615-14-4-391. [DOI] [PubMed] [Google Scholar]
- Johnston R. B., Jr, Baehner R. L. Chronic granulomatous disease: correlation between pathogenesis and clinical findings. Pediatrics. 1971 Nov;48(5):730–739. [PubMed] [Google Scholar]
- Johnston R. B., Newman S. L. Chronic granulomatous disease. Pediatr Clin North Am. 1977 May;24(2):365–376. doi: 10.1016/s0031-3955(16)33424-1. [DOI] [PubMed] [Google Scholar]
- Kasper D. L., Hayes M. E., Reinap B. G., Craft F. O., Onderdonk A. B., Polk B. F. Isolation and identification of encapsulated strains of Bacteroides fragilis. J Infect Dis. 1977 Jul;136(1):75–81. doi: 10.1093/infdis/136.1.75. [DOI] [PubMed] [Google Scholar]
- Kasper D. L., Onderdonk A. B., Reinap B. G., Linberg A. A. Variations of Bacteroides fragilis with in vitro passage: presence of an outer membrane-associated glycan and loss of capsular antigen. J Infect Dis. 1980 Nov;142(5):750–756. doi: 10.1093/infdis/142.5.750. [DOI] [PubMed] [Google Scholar]
- Klebanoff S. J. Antimicrobial mechanisms in neutrophilic polymorphonuclear leukocytes. Semin Hematol. 1975 Apr;12(2):117–142. [PubMed] [Google Scholar]
- Lindberg A. A., Berthold P., Nord C. E., Weintraub A. Encapsulated strains of Bacteroides fragilis in clinical specimens. Med Microbiol Immunol. 1979 Mar 13;167(1):29–36. doi: 10.1007/BF02123293. [DOI] [PubMed] [Google Scholar]
- Mandell G. L. Bactericidal activity of aerobic and anaerobic polymorphonuclear neutrophils. Infect Immun. 1974 Feb;9(2):337–341. doi: 10.1128/iai.9.2.337-341.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McRipley R. J., Sbarra A. J. Role of the phagocyte in host-parasite interactions. XI. Relationship between stimulated oxidative metabolism and hydrogen peroxide formation, and intracellular killing. J Bacteriol. 1967 Nov;94(5):1417–1424. doi: 10.1128/jb.94.5.1417-1424.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Okamura N., Spitznagel J. K. Outer membrane mutants of Salmonella typhimurium LT2 have lipopolysaccharide-dependent resistance to the bactericidal activity of anaerobic human neutrophils. Infect Immun. 1982 Jun;36(3):1086–1095. doi: 10.1128/iai.36.3.1086-1095.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Onderdonk A. B., Kasper D. L., Cisneros R. L., Bartlett J. G. The capsular polysaccharide of Bacteroides fragilis as a virulence factor: comparison of the pathogenic potential of encapsulated and unencapsulated strains. J Infect Dis. 1977 Jul;136(1):82–89. doi: 10.1093/infdis/136.1.82. [DOI] [PubMed] [Google Scholar]
- Polk B. F., Kasper D. L. Bacteroides fragilis subspecies in clinical isolates. Ann Intern Med. 1977 May;86(5):569–571. doi: 10.7326/0003-4819-86-5-569. [DOI] [PubMed] [Google Scholar]
- Quie P. G. Bactericidal function of human polymorphonuclear leukocytes. E. Mead Johnson Award Address. Pediatrics. 1972 Aug;50(2):264–270. [PubMed] [Google Scholar]
- Rest R. F., Cooney M. H., Spitznagel J. K. Susceptibility of lipopolysaccharide mutants to the bactericidal action of human neutrophil lysosomal fractions. Infect Immun. 1977 Apr;16(1):145–151. doi: 10.1128/iai.16.1.145-151.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Selvaraj R. J., Sbarra A. J. Relationship of glycolytic and oxidative metabolism to particle entry and destruction in phagocytosing cells. Nature. 1966 Sep 17;211(5055):1272–1276. doi: 10.1038/2111272a0. [DOI] [PubMed] [Google Scholar]
- Simon G. L., Klempner M. S., Kasper D. L., Gorbach S. L. Alterations in opsonophagocytic killing by neutrophils of Bacteroides fragilis associated with animal and laboratory passage: effect of capsular polysaccharide. J Infect Dis. 1982 Jan;145(1):72–77. doi: 10.1093/infdis/145.1.72. [DOI] [PubMed] [Google Scholar]
- Tagesson C., Stendahl O. Influence of the cell surface lipopolysaccharide structure of Salmonella typhimurium on resistance to intracellular bactericidal systems. Acta Pathol Microbiol Scand B Microbiol Immunol. 1973 Aug;81(4):473–480. doi: 10.1111/j.1699-0463.1973.tb02232.x. [DOI] [PubMed] [Google Scholar]
- Weiss J., Beckerdite-Quagliata S., Elsbach P. Resistance of gram-negative bacteria to purified bactericidal leukocyte proteins: relation to binding and bacterial lipopolysaccharide structure. J Clin Invest. 1980 Mar;65(3):619–628. doi: 10.1172/JCI109707. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Weiss J., Victor M., Stendhal O., Elsbach P. Killing of gram-negative bacteria by polymorphonuclear leukocytes: role of an O2-independent bactericidal system. J Clin Invest. 1982 Apr;69(4):959–970. doi: 10.1172/JCI110535. [DOI] [PMC free article] [PubMed] [Google Scholar]