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. 2005;4(3):152–161. doi: 10.1016/S0899-3467(07)60124-4

Effects of the homeopathic remedy arnica on attenuating symptoms of exercise-induced muscle soreness

Julie A Plezbert a,*, Jeanmarie R Burke b
PMCID: PMC2647043  PMID: 19674657

Abstract

Objective

To evaluate the clinical efficacy of Arnica at a high potency (200c), on moderating delayed onset muscle soreness and accompanying symptoms of muscle dysfunction.

Methods

Twenty subjects completed a maximal eccentric exercise protocol with the non-dominate elbow flexors to induce delayed onset muscle soreness. Either Arnica or placebo tablets were administered in a random, double- blinded fashion immediately after exercise and at 24 hours and 72 hours after exercise. Before exercise, immediately post-exercise, and at 24, 48, 72, and 96 hours post-exercise, assessments of delayed onset muscle soreness and muscle function included: 1) muscle soreness and functional impairment; 2) maximum voluntary contraction torque; 3) muscle swelling; and 4) range of motion tests to document spontaneous muscle shortening and muscle shortening ability. Blood samples drawn before exercise and at 24, 48, and 96 hours after exercise were used to measure muscle enzymes as indirect indices of muscle damage.

Results

Regardless of the intervention, the extent of delayed onset muscle soreness and elevations in muscle enzymes were similar on the days following the eccentric exercise protocol. The post-exercise time profiles of decreases in maximum voluntary contraction torque and muscle shortening ability and increases in muscle swelling and spontaneous muscle shortening were similar for each treatment intervention.

Conclusions

The results of this study did not substantiate the clinical efficacy of Arnica at a high potency on moderating delayed onset muscle soreness and accompanying symptoms of muscle dysfunction. Despite the findings of this study, future investigations on the clinical efficacy of homeopathic interventions should consider incorporating research strategies that emphasize differential therapeutics for each patient rather than treating a specific disease or symptom complex, such as DOMS, with a single homeopathic remedy.

Key Indexing Terms: Homeopathy; Arnica; Muscle, Skeletal; Exercise; Delayed Onset Muscle Soreness

Footnotes

Sources of support: Dolisos, Inc. donated the homeopathic remedy, Arnica, and the placebo tablets. There was no financial gain or arrangements with this pharmacy.

References

  • 1.Kayne SB. Homeopathic pharmacy: an introduction and handbook. Churchill Livingstone; New York: 1997. [Google Scholar]
  • 2.Vallance AK. Can biological activity be maintained at ultra-high dilution? An overview of homeopathy, evidence, and Bayesian philosophy. J Altern Complement Med. 1998;4:49–76. doi: 10.1089/acm.1998.4.1-49. [DOI] [PubMed] [Google Scholar]
  • 3.Castro M. The complete handbook of homeopathy. St. Martin's Press; New York: 1991. [Google Scholar]
  • 4.Tyler ML. Homeopathic drug pictures. Homeopathic Book Services; England: 2004. [Google Scholar]
  • 5.Vermeulen F. Concordant material medica. 1st ed. Merlijn Publishers; Netherlands: 1994. [Google Scholar]
  • 6.Bernard J. Potency in homeopathic prescribing: penetrating the mystique (part 1) Simillimum. 1999;XII:61–72. [Google Scholar]
  • 7.Bernard J. Potency in homeopathic prescribing: survey results and conclusions (part 2) Simillimum. 2000;XIII:101–110. [Google Scholar]
  • 8.Merrell WC, Shalts E. Homeopathy. Med Clin North Am. 2002;86:47–62. doi: 10.1016/s0025-7125(03)00071-3. [DOI] [PubMed] [Google Scholar]
  • 9.Clarkson PM, Nosaka K, Braun B. Muscle function after exerciseinduced muscle damage and rapid adaptation. Med Sci Sports Exerc. 1992;24:512–520. [PubMed] [Google Scholar]
  • 10.Clarkson PM, Sayers SP. Etiology of exercise-induced muscle damage. Can J Appl Physiol. 1999;24:234–248. doi: 10.1139/h99-020. [DOI] [PubMed] [Google Scholar]
  • 11.Nosaka K, Clarkson PM. Changes in indicators of inflammation after eccentric exercise of the elbow flexors. Med Sci Sports Exerc. 1996;28:953–961. doi: 10.1097/00005768-199608000-00003. [DOI] [PubMed] [Google Scholar]
  • 12.Nosaka K, Clarkson PM. Variability in serum creatine kinase response after eccentric exercise of the elbow flexors. Int J Sports Med. 1996;17:120–127. doi: 10.1055/s-2007-972819. [DOI] [PubMed] [Google Scholar]
  • 13.Jawara N, Lewith GT, Vickers AJ, Mullee MA, Smith C. Homeopathic Arnica and Rhus toxicodendron for delayed onset muscle soreness. Br Homeopathic J. 1997;86:10–15. [Google Scholar]
  • 14.Tuten C, McClung J. Reducing muscle soreness with Arnica montana. Alternat Complement Ther. 1999;5:369–372. [Google Scholar]
  • 15.Vickers AJ, Fisher P, Smith C, Wyllie SE, Lewith GT. Homoeopathy for delayed onset muscle soreness: a randomised double blind placebo controlled trial. Br J Sports Med. 1997;31:304–307. doi: 10.1136/bjsm.31.4.304. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 16.Tveiten D, Bruset S. Effect of Arnica D30 in marathon runners. Pooled results from two double-blind placebo controlled studies. Homeopathy. 2003;92:187–189. doi: 10.1016/j.homp.2003.03.001. [DOI] [PubMed] [Google Scholar]
  • 17.Tveiten D, Bruset S, Borchgrevink CF, Lohne K. Effect of Arnica D 30 on hard physcial exercise. Tidskr Nor Loegeforen. 1991;111:3630–3631. [PubMed] [Google Scholar]
  • 18.Tveiten D, Bruset S, Borchgrevink CF, Norseth J. Effects of the homoepathic remedy Arnica D30 on marathon runners: A randomized, double-blind study during the 1995 Oslo Marathon. Complement Ther Med. 1998;6:71–74. [Google Scholar]
  • 19.Vickers AJ, Fisher P, Smith C, Wyllie SE, Rees R. Homeopathic Arnica 30x is ineffective for muscle soreness after long-distance running: a randomized, double-blind, placebo-controlled trial. Clin J Pain. 1998;14:227–231. doi: 10.1097/00002508-199809000-00009. [DOI] [PubMed] [Google Scholar]
  • 20.Gulick DT, Kimura IF, Sitler M, Paolone A, Kelly JD. Various treatment techniques on signs and symptoms of delayed onset muscle soreness. J Athl Train. 1996;31:145–152. [PMC free article] [PubMed] [Google Scholar]
  • 21.Cheung K, Hume P, Maxwell L. Delayed onset muscle soreness: treatment strategies and performance factors. Sports Med. 2003;33:145–164. doi: 10.2165/00007256-200333020-00005. [DOI] [PubMed] [Google Scholar]
  • 22.Ernst E, Pittler MH. Efficacy of homeopathic Arnica: a systematic review of placebo-controlled clinical trials. Arch Surg. 1998;133:1187–1190. doi: 10.1001/archsurg.133.11.1187. [DOI] [PubMed] [Google Scholar]
  • 23.Freeman LW. Homeopathy: Like cures Like. In: Freeman LW, Lawlis FG, editors. Complementary and alternative medicine: a research based approach. Mosby; St. Louis: 2001. pp. 345–360. [Google Scholar]
  • 24.Tonelli MR, Callahan TC. Why alternative medicine cannot be evidence-based. Acad Med. 2001;76:1213–1220. doi: 10.1097/00001888-200112000-00011. [DOI] [PubMed] [Google Scholar]
  • 25.Ernst E. The benefits of Arnica: 16 case reports. Homeopathy. 2003;92:217–219. doi: 10.1016/j.homp.2003.07.001. [DOI] [PubMed] [Google Scholar]
  • 26.Thomas KJ, Fitter MJ. Evaluating complementary therapies for use in the National Health Service: ‘horses for courses’. Part 2: alternative research strategies. Complement Ther Med. 1997;5:94–98. [Google Scholar]
  • 27.Verhoef MJ, Casebeer AL, Hilsden RJ. Assessing efficacy of complementary medicine: adding qualitative research methods to the “gold standard”. J Altern Complement Med. 2002;8:275–281. doi: 10.1089/10755530260127961. [DOI] [PubMed] [Google Scholar]
  • 28.Carter B. Methodological issues and complementary therapies: researching intangibles? Complement Ther Nurs Midwifery. 2003;9:133–139. doi: 10.1016/S1353-6117(03)00042-8. [DOI] [PubMed] [Google Scholar]
  • 29.Sayers SP, Clarkson PM, Rouzier PA, Kamen G. Adverse events associated with eccentric exercise protocols: six case studies. Med Sci Sports Exerc. 1999;31:1697–1702. doi: 10.1097/00005768-199912000-00002. [DOI] [PubMed] [Google Scholar]
  • 30.Byrne C, Twist C, Eston R. Neuromuscular function after exerciseinduced muscle damage: theoretical and applied implications. Sports Med. 2004;34:49–69. doi: 10.2165/00007256-200434010-00005. [DOI] [PubMed] [Google Scholar]
  • 31.Proske U, Morgan DL. Muscle damage from eccentric exercise: mechanism, mechanical signs, adaptation and clinical applications. J Physiol. 2001;537:333–345. doi: 10.1111/j.1469-7793.2001.00333.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 32.Clarkson PM, Hubal MJ. Exercise-induced muscle damage in humans. Am J Phys Med Rehabil. 2002;81:S52–S69. doi: 10.1097/00002060-200211001-00007. [DOI] [PubMed] [Google Scholar]

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