Abstract
Objective
The objective of this study is to use randomized controlled research design to investigate the effect of an exercise program and custom-made flexible orthotics on heart rate variability and blood pressure at varying stages of exercise over a 5-month period.
Methods
Thirteen ping-pong players were recruited and randomly assigned into control and experimental groups. Both groups had the same exercise program, and only the experimental group wore custom-made flexible orthotics. Exercise effects were compared before and after the training using heart rate variability and blood pressure. The study lasted 5 months with 1 data collection per month except in the fourth month.
Results
Ten male players (6 in the experimental group) completed the study. The average age of the participants was 44 ± 16 years. The blood pressure in the experimental group significantly decreased after the 5-month study period and after each exercise session. The blood pressure did not change significantly after each exercise session in the control group. The heart rate was significantly increased immediately after exercise and remained at a higher level after the 20 minutes of rest at the end of each day's exercise session. The average resting heart rate decreased from 69.7 ± 1.708 to 66.8 ± 4.480 (P < .05) in the experimental group but increased from 69.7 ± 1.708 to 90.7 ± 2.808 (P > .05) in the control group. The total power reflecting the total autonomic activity was significantly decreased immediately after exercise and after the 20-minute rest period at the end of the exercise session in both the control and experimental groups.
Conclusions
There were positive changes in cardiac and vascular autonomic regulations with exercise training when combined with foot orthotics.
Introduction
Research evidence has suggested that the autonomic nervous system activities are affected by exercise in normal and disease conditions.1-4 Questions remain as to how trained athletes' heart rate variability (HRV) and blood pressure (BP) change at different stages of exercise, namely, before, during, and after an exercise program. Because BP is strongly influenced by the autonomic nervous system in daily activities,5 it is interesting to investigate the interaction of the autonomic nervous system with BP under an exercise program. It is known that long-term BP is determined by fluid homeostasis.5 Short-term BP changes during daily activities are not reliable indicators of BP changes.5,6 Therefore, this study was designed to investigate both short-term (1 day) and long-term (5 months) continuous exercise program on BP and HRV in recreational athletes.
There are many studies on the effect of exercise on BP and HRV. Sharma and Deepak7 explored the possibility of a short duration of supervised physical training on cardiovascular performance and attempted to look into the changes in the autonomic tone as assessed by HRV. They studied 25 healthy adult male subjects who underwent 15 days of moderate physical training on a bicycle ergometer. Heart rate (HR) and BP response to exercise and during recovery were monitored and autonomic activity (tone) was assessed by HRV in a resting condition, and all the parameters were compared before and after physical training. Heart rate response to graded exercise on the bicycle ergometer showed a significant decrease at the second, third, fifth, and sixth minute during exercise after physical training, and systolic BP response showed a significant decrease at fourth, fifth, and sixth minute during exercise after physical training. They concluded that even a short duration of physical training results in favorable cardiovascular performance and it may be ascribed to autonomic modulation.
Information regarding the effect of a custom-made flexible orthotics on the autonomic nervous system and BP is very limited. However, this area of research is directly related to athletic performance in 2 important aspects. The first is the direct effect of the autonomic nervous system activities on athletic performance, BP and HRV. The second is the comfort of shoes with corrective orthotics that promote athletic performance and reduce existing pain.8,9 For the first aspect, no study has documented that custom-made flexible orthotics affect the autonomic nervous system function. For the second aspect, there are many studies showing improved performance of workers using orthotics but less evidence for athletes.10-14
The purpose of this study is to use a randomized controlled research design to investigate the effect of an exercise program and custom-made flexible orthotics on HRV and BP at varying stages of exercise. The hypothesis was that exercise and custom-made orthotics have a positive impact on the HRV and BP. Therefore, the null hypothesis was that exercise and custom-made flexible orthotics would not induce positive changes in HRV and BP during the study period.
Methods
Design
This is a randomized controlled study. A random table was used for subject assignment to either the experimental or the control group.15 Both groups had the same exercise program, and only the experimental group worn custom-made flexible orthotics. The exercise effects were compared before and after the training. This study was approved by the Logan College of Chiropractic Institutional Review Board (Chesterfield, MO). All subjects read and signed institutional review board–approved informed consent documents before they underwent any study-related procedure. No sample size estimate was used in this pilot study because of the size limitation of the sports club.
Subjects
Subjects from different racial, sex, and age groups were recruited in this study. Each subject was a ping-pong club member for the previous 5 years and was an active member in the club. Only subjects who played at least twice a week or no less than 6 hours per week were included. Any individual with coronary heart diseases, serious uncontrolled hypertension, or other diseases, such as osteoporosis, were excluded from the study. All players agreed to participate in the study without monetary compensation.
Method
Heart rate variability
Biocom's (Biocom, Seattle, Wash) Heart Rhythm Scanner was used in the HRV data collection with digital signal processing software. The heart scanner records electrocardiographic (ECG) signal, computing the instantaneous changes of HRV after each recording session. The heart rhythm scanner is an ECG unit that connects the unit to the subjects through 3 small electrodes that attached to the left arm, right arm, and left leg. No additional gels were needed for the electrodes. Special care was given to clean the skin surface to improve skin conductance. Data cleaning techniques were used to remove noise in the ECG signals to improve the quality of HRV measurements. This included checking each ECG tracing to make sure that accurate ECG R-R intervals were recorded for HRV analysis.
Blood pressure
BIOPAC (BIOPAC Systems Inc, Goleta, Calif) BP measurement equipment was used for the study. The device uses manual control for BP measurements to reduce instrumental errors.
Custom-made flexible orthotics
All foot orthotics were custom-made first by scanning the subjects' feet in the research laboratory, and necessary information was sent to Foot Levelers (Roanoke, Va) for fabrication. It took about 6 to 8 days to receive the orthotics after the order was made. The custom-made flexible orthotics were fit to Foot Levelers's standard sports shoes for comfort and easy application. This eliminated the need for athletes to fit the orthotics to their own shoes.
Study protocol
The study lasted 5 months with 1 data collection per month except in the fourth month. During each data collection, BP and HRV data were collected 3 times (ie, baseline, between games, after games). The ping-pong club met twice a week on Tuesday and Thursday between 6:30 and 10:00 pm on a regular basis. Each player was allowed 10 minutes of warm-up before competitive play. The baseline HRV and BP were recorded before the warm-up period. After 1 player played with 2 other players, the between-the-game data were collected right after the second game. No rest was allowed for this data collection to detect the peak HR and BP changes. The third data collection of HRV and BP was at the end of the playing period when all subjects were to have rested for at least 20 minutes to cool off from the games before the data were collected.
Data collection
The data were collected by the researcher on the study site from 6:30 to 10:00 pm regularly on Tuesdays and Thursdays. The manual BP measurements provided reliable readings of the subjects' BP. The HRV recording was an objective reading of the subjects' real-time ECG, which was believed to be reliable. There were no computer crashes or any mechanical damages to any research equipment during the data collection period.
Statistical analysis
All continuous data were expressed as mean ± SD. Student t test was used for comparisons of continuous variables measured in the study. Statistical analysis was performed using SPSS 12 (SPSS Inc, Chicago, Ill). A probability of less than .05 was considered significant.
Results
Thirteen ping-pong players were recruited and 10 player's data were included in the data analysis (10 male, 6 in the experimental group). Three players left the club because of job transfer or other personal reasons while participating in the study (Fig 1). The average age of the participants was 44 ± 16 years. During the 5-month study period, there were no adverse events that occurred with or without wearing the foot orthotics.
Fig 1.
Study flow chart.
The BP responses before, during, and after exercise in the 5-month study are shown in Tables 1 and 2. The BP in the experimental subjects was significantly decreased after the 5-month study period. Significant BP decrease was observed in the experimental group before, during, and after each exercise session (Fig 2). The BP did not decrease before, during, and after each exercise session in the control group (Fig 3).
Table 1.
Five-month BP response before, during, and after exercise in the experimental group
| Experimental Group |
|||||||
|---|---|---|---|---|---|---|---|
| Before EX |
During EX |
After EX |
|||||
| Systolic | Diastolic | Systolic | Diastolic | Systolic | Diastolic | ||
| First Month | Mean | 128.000 | 84.167 | 119.667 | 82.333 | 116.667 | 83.833 |
| SD | 11.314 | 3.920 | 10.614 | 4.082 | 9.180 | 3.488 | |
| t | 0.026 | 0.194 | 0.025 | 0.809 | |||
| Second Month | Mean | 122.667 | 82.833 | 117.000 | 81.667 | 118.333 | 80.333 |
| SD | 7.659 | 5.456 | 5.762 | 3.670 | 7.528 | 1.966 | |
| t | 0.137 | 0.545 | 0.189 | 0.286 | |||
| Third Month | Mean | 125.200 | 84.400 | 117.200 | 84.400 | 113.600 | 81.600 |
| SD | 10.354 | 4.336 | 12.215 | 6.066 | 12.837 | 3.578 | |
| t | 0.025 | 1.000 | 0.035 | 0.108 | |||
| Fifth Month | Mean | 121.167 | 81.667 | 119.000 | 81.000 | 111.667 | 80.333 |
| SD | 2.041 | 2.658 | 1.673 | 2.449 | 7.528 | 4.457 | |
| t | 0.108 | 0.709 | 0.035 | 0.328 | |||
EX, Exercise.
Table 2.
Five-month BP response before, during, and after exercise in the control group
| Control Group |
|||||||
|---|---|---|---|---|---|---|---|
| Before EX |
During EX |
After EX |
|||||
| Systolic | Diastolic | Systolic | Diastolic | Systolic | Diastolic | ||
| First Month | Mean | 126.833 | 83.000 | 123.500 | 84.667 | 126.667 | 83.667 |
| SD | 14.148 | 6.293 | 14.963 | 6.772 | 8.733 | 6.623 | |
| t | 0.337 | 0.185 | 0.952 | 0.465 | |||
| Second Month | Mean | 125.333 | 83.333 | 121.000 | 82.333 | 120.000 | 84.333 |
| SD | 8.641 | 5.317 | 7.127 | 4.457 | 6.325 | 3.882 | |
| t | 0.290 | 0.415 | 0.170 | 0.741 | |||
| Third Month | Mean | 124.000 | 82.000 | 125.500 | 80.833 | 121.333 | 81.167 |
| SD | 7.899 | 5.060 | 10.913 | 4.834 | 11.075 | 5.456 | |
| t | 0.479 | 0.135 | 0.371 | 0.259 | |||
| Fifth Month | Mean | 118.333 | 82.667 | 114.000 | 78.000 | 113.333 | 77.333 |
| SD | 13.292 | 5.888 | 14.859 | 5.367 | 13.003 | 6.282 | |
| t | 0.071 | 0.052 | 0.042 | 0.072 | |||
Fig 2.
Blood pressure changes in the experimental group.
Fig 3.
Blood pressure changes in the control group.
The HRV responses are shown in Tables 3-10. The HR was significantly increased immediately after exercise. Many players' HRs were more than 150 beats per minute immediately after the 2 games and gradually decreased during the 5 minutes of HRV data collection. The decrease of HR during the resting period was uneven between the players. Younger players' HRs decreased faster than older players. Among the older players with similar ages, the decrease in HR was related to the total power of the individual. Subjects with lower total power or a small HRV had slower return of HR. Individuals with higher total power decreased HR faster after exercise. The HR for most players remained at a higher level after the 20 minutes of rest at the end of each day's exercise session. Some players did not show significant HR reduction during the 20-minute rest period. The average resting HR (baseline HR before each data collection) was decreased from 69.7 ± 1.708 to 66.8 ± 4.480 (P < .05) in the experimental group but increased from 69.7 ± 1.708 to 90.7 ± 2.808 (P > .05) in the control group. The total power reflecting the total autonomic activity was significantly decreased immediately after exercise and after the 20-minute rest period at the end of the exercise session in both the control and experimental groups.
Table 3.
Heart rate variability of the experimental group in the first month
| First Month | Experimental Group |
|||||||
|---|---|---|---|---|---|---|---|---|
| Before |
During |
After |
||||||
| Mean | SD | Mean | SD | t | Mean | SD | t | |
| Heart Rate | 69.700 | 1.709 | 106.800 | 4.613 | 0.008 | 86.733 | 9.834 | 0.117 |
| Mean RR | 861.300 | 21.328 | 562.433 | 24.188 | 0.006 | 697.900 | 82.071 | 0.103 |
| SDNN | 53.967 | 15.653 | 36.900 | 4.900 | 0.287 | 32.333 | 16.772 | 0.296 |
| RMS-SD | 37.300 | 4.453 | 16.070 | 6.109 | 0.059 | 22.600 | 12.917 | 0.218 |
| Total Power | 822.400 | 358.289 | 68.567 | 22.743 | 0.062 | 495.233 | 622.474 | 0.576 |
| VLF | 306.700 | 149.266 | 26.167 | 5.248 | 0.087 | 159.367 | 177.479 | 0.512 |
| LF | 367.167 | 170.553 | 31.100 | 18.460 | 0.062 | 291.833 | 410.820 | 0.791 |
| HF | 148.500 | 98.144 | 11.300 | 2.740 | 0.131 | 44.067 | 34.683 | 0.265 |
| LF Norm | 71.733 | 7.267 | 69.367 | 14.545 | 0.778 | 75.933 | 12.889 | 0.394 |
| HF Norm | 28.267 | 7.267 | 30.700 | 14.660 | 0.774 | 24.067 | 12.889 | 0.394 |
| LF/HF | 2.700 | 1.127 | 2.700 | 1.400 | 1.000 | 4.533 | 3.980 | 0.384 |
RR, R-R interval; SDNN, SD of the normal-to-normal heartbeats; RMS, root mean squared; VLF, very low frequency; LF, low frequency: HF, high frequency; Norm, normalized.
Table 4.
Heart rate variability of the experimental group in the second month
| Second Month | Experimental Group |
|||||||
|---|---|---|---|---|---|---|---|---|
| Before |
During |
After |
||||||
| Mean | SD | Mean | SD | t | Mean | SD | t | |
| Heart Rate | 71.100 | 4.457 | 95.960 | 17.534 | 0.028 | 85.650 | 7.566 | 0.327 |
| Mean RR | 846.740 | 56.027 | 642.060 | 116.272 | 0.009 | 703.550 | 62.296 | 0.316 |
| SDNN | 47.200 | 6.256 | 33.340 | 10.062 | 0.222 | 33.350 | 9.122 | 0.100 |
| RMS-SD | 35.875 | 9.936 | 21.620 | 9.673 | 0.183 | 37.400 | 17.253 | 0.608 |
| Total Power | 620.250 | 132.641 | 205.720 | 178.776 | 0.046 | 239.900 | 91.217 | 0.053 |
| VLF | 360.375 | 114.015 | 118.220 | 105.503 | 0.090 | 54.950 | 30.618 | 0.280 |
| LF | 184.975 | 95.149 | 57.980 | 49.501 | 0.047 | 103.600 | 36.204 | 0.254 |
| HF | 74.875 | 43.573 | 29.500 | 25.605 | 0.297 | 81.350 | 85.631 | 0.546 |
| LF Norm | 68.325 | 16.541 | 68.040 | 9.795 | 0.929 | 63.300 | 22.203 | 0.358 |
| HF Norm | 31.675 | 16.541 | 31.960 | 9.795 | 0.929 | 36.700 | 22.203 | 0.358 |
| LF/HF | 2.900 | 1.917 | 2.440 | 1.448 | 0.860 | 2.350 | 2.051 | 0.049 |
Table 5.
Heart rate variability of the experimental group in the third month
| Third Month | Experimental Group |
|||||||
|---|---|---|---|---|---|---|---|---|
| Before |
During |
After |
||||||
| Mean | SD | Mean | SD | t | Mean | SD | t | |
| Heart Rate | 66.800 | 4.480 | 101.525 | 6.663 | 0.006 | 93.550 | 4.273 | 0.002 |
| Mean RR | 901.425 | 60.979 | 592.825 | 37.175 | 0.006 | 642.300 | 29.380 | 0.003 |
| SDNN | 62.175 | 20.663 | 33.325 | 3.195 | 0.067 | 33.150 | 9.112 | 0.111 |
| RMS-SD | 37.875 | 10.135 | 13.850 | 10.414 | 0.069 | 25.975 | 6.589 | 0.182 |
| Total Power | 1228.200 | 705.731 | 161.925 | 146.018 | 0.066 | 265.375 | 191.254 | 0.098 |
| VLF | 575.525 | 252.195 | 70.575 | 43.490 | 0.029 | 114.625 | 110.537 | 0.075 |
| LF | 527.100 | 384.792 | 68.950 | 73.431 | 0.110 | 112.100 | 63.155 | 0.117 |
| HF | 125.525 | 80.131 | 22.375 | 34.695 | 0.136 | 38.575 | 33.418 | 0.185 |
| LF Norm | 78.875 | 6.035 | 83.025 | 9.414 | 0.492 | 75.250 | 7.942 | 0.508 |
| HF Norm | 21.100 | 6.067 | 16.975 | 9.414 | 0.495 | 24.750 | 7.942 | 0.506 |
| LF/HF | 4.025 | 1.307 | 6.125 | 3.135 | 0.208 | 3.475 | 1.861 | 0.653 |
Table 6.
Heart rate variability of the experimental group in the fifth month
| Fifth Month | Experimental Group |
|||||||
|---|---|---|---|---|---|---|---|---|
| Before |
During |
After |
||||||
| Mean | SD | Mean | SD | t | Mean | SD | t | |
| Heart Rate | 75.517 | 11.303 | 104.483 | 16.036 | 0.001 | 95.000 | 14.027 | 0.023 |
| Mean RR | 811.350 | 137.696 | 585.167 | 85.783 | 0.001 | 642.660 | 92.990 | 0.019 |
| SDNN | 47.150 | 13.036 | 51.017 | 46.899 | 0.870 | 32.360 | 13.230 | 0.202 |
| RMS-SD | 33.700 | 15.620 | 54.350 | 70.008 | 0.538 | 24.420 | 13.985 | 0.330 |
| Total Power | 566.017 | 315.657 | 265.033 | 419.101 | 0.313 | 348.000 | 243.786 | 0.401 |
| VLF | 234.500 | 141.543 | 143.200 | 227.547 | 0.523 | 177.400 | 197.433 | 0.629 |
| LF | 261.117 | 175.158 | 72.200 | 110.187 | 0.125 | 134.140 | 95.474 | 0.252 |
| HF | 70.417 | 37.963 | 49.583 | 81.919 | 0.654 | 36.440 | 47.250 | 0.334 |
| LF Norm | 76.400 | 8.389 | 62.033 | 9.615 | 0.095 | 83.200 | 9.743 | 0.362 |
| HF Norm | 23.583 | 8.386 | 37.967 | 9.615 | 0.094 | 16.740 | 9.746 | 0.354 |
| LF/HF | 3.983 | 2.751 | 1.800 | 0.727 | 0.162 | 6.300 | 3.029 | 0.384 |
Table 7.
Heart rate variability of the control group in the first month
| First Month | Control Group |
|||||||
|---|---|---|---|---|---|---|---|---|
| Before |
During |
After |
||||||
| Mean | SD | Mean | SD | t | Mean | SD | t | |
| Heart Rate | 69.700 | 1.709 | 117.567 | 4.891 | 0.031 | 100.767 | 7.304 | 0.185 |
| Mean RR | 861.300 | 21.328 | 510.800 | 20.756 | 0.040 | 597.500 | 41.830 | 0.177 |
| SDNN | 53.967 | 15.653 | 36.700 | 12.950 | 0.821 | 21.267 | 11.296 | 0.431 |
| RMS-SD | 37.300 | 4.453 | 16.733 | 8.776 | 0.086 | 14.800 | 8.107 | 0.196 |
| Total Power | 822.400 | 358.289 | 44.600 | 12.401 | 0.162 | 122.000 | 138.609 | 0.352 |
| VLF | 306.700 | 149.266 | 27.633 | 17.789 | 0.236 | 31.367 | 22.912 | 0.281 |
| LF | 367.167 | 170.553 | 9.133 | 6.028 | 0.199 | 77.700 | 102.561 | 0.794 |
| HF | 148.500 | 98.144 | 7.800 | 6.056 | 0.157 | 12.933 | 13.271 | 0.304 |
| LF Norm | 71.733 | 7.267 | 52.567 | 33.739 | 0.634 | 81.300 | 5.575 | 0.179 |
| HF Norm | 28.267 | 7.267 | 47.433 | 33.739 | 0.634 | 18.700 | 5.575 | 0.179 |
| LF/HF | 2.700 | 1.127 | 3.500 | 5.200 | 0.706 | 4.733 | 1.986 | 0.214 |
Table 8.
Heart rate variability of the control group in the second month
| Second Month | Control Group |
|||||||
|---|---|---|---|---|---|---|---|---|
| Before |
During |
After |
||||||
| Mean | SD | Mean | SD | t | Mean | SD | t | |
| Heart Rate | 79.100 | 7.661 | 106.525 | 11.281 | 0.010 | 102.150 | 1.768 | 0.185 |
| Mean RR | 763.550 | 71.020 | 568.025 | 61.217 | 0.010 | 587.600 | 10.324 | 0.235 |
| SDNN | 40.400 | 12.147 | 20.450 | 6.011 | 0.094 | 28.500 | 3.111 | 0.256 |
| RMS-SD | 28.475 | 3.550 | 15.400 | 8.730 | 0.114 | 15.350 | 10.960 | 0.473 |
| Total Power | 475.600 | 340.010 | 84.575 | 108.809 | 0.111 | 99.750 | 9.546 | 0.349 |
| VLF | 217.175 | 205.756 | 22.525 | 21.053 | 0.158 | 56.550 | 42.639 | 0.180 |
| LF | 196.500 | 120.124 | 51.000 | 84.403 | 0.061 | 31.450 | 20.294 | 0.408 |
| HF | 61.925 | 37.776 | 11.025 | 6.917 | 0.102 | 11.750 | 12.799 | 0.313 |
| LF Norm | 75.000 | 5.855 | 65.025 | 30.745 | 0.531 | 77.600 | 12.587 | 0.550 |
| HF Norm | 25.000 | 5.855 | 34.975 | 30.745 | 0.531 | 22.400 | 12.587 | 0.550 |
| LF/HF | 3.200 | 1.143 | 5.825 | 6.033 | 0.414 | 4.300 | 2.970 | 0.500 |
Table 9.
Heart rate variability of the control group in the third month
| Third Month | Control Group |
|||||||
|---|---|---|---|---|---|---|---|---|
| Before |
During |
After |
||||||
| Mean | SD | Mean | SD | t | Mean | SD | t | |
| Heart Rate | 90.700 | 2.828 | 114.250 | 12.657 | 0.183 | 106.550 | 5.020 | 0.062 |
| Mean RR | 661.950 | 20.435 | 528.300 | 58.548 | 0.127 | 563.600 | 26.446 | 0.027 |
| SDNN | 32.150 | 0.212 | 24.800 | 1.273 | 0.090 | 29.750 | 3.323 | 0.472 |
| RMS-SD | 22.700 | 0.849 | 15.300 | 10.182 | 0.517 | 14.100 | 10.465 | 0.477 |
| Total Power | 386.400 | 223.021 | 92.850 | 94.116 | 0.192 | 294.900 | 65.902 | 0.561 |
| VLF | 140.250 | 100.904 | 53.300 | 55.013 | 0.227 | 163.050 | 113.632 | 0.239 |
| LF | 206.100 | 107.480 | 34.050 | 40.941 | 0.170 | 116.250 | 34.719 | 0.536 |
| HF | 39.950 | 14.637 | 5.450 | 1.768 | 0.206 | 15.600 | 13.011 | 0.431 |
| LF Norm | 83.200 | 2.404 | 68.550 | 35.709 | 0.646 | 89.250 | 6.010 | 0.254 |
| HF Norm | 16.800 | 2.404 | 31.450 | 35.709 | 0.646 | 10.750 | 6.010 | 0.254 |
| LF/HF | 5.000 | 0.849 | 7.950 | 10.112 | 0.731 | 10.050 | 6.152 | 0.407 |
Table 10.
Heart rate variability of the control group in the fifth month
| Fifth Month | Control Group |
|||||||
|---|---|---|---|---|---|---|---|---|
| Before |
During |
After |
||||||
| Mean | SD | Mean | SD | t | Mean | SD | t | |
| Heart Rate | 75.425 | 5.309 | 106.200 | 8.283 | 0.002 | 92.800 | 6.280 | 0.000 |
| Mean RR | 798.400 | 56.651 | 567.525 | 44.571 | 0.001 | 648.800 | 45.556 | 0.000 |
| SDNN | 45.000 | 11.265 | 34.700 | 3.477 | 0.089 | 33.650 | 12.600 | 0.101 |
| RMS-SD | 24.375 | 12.654 | 19.225 | 9.506 | 0.622 | 19.050 | 5.807 | 0.373 |
| Total Power | 824.050 | 494.609 | 103.700 | 53.225 | 0.051 | 458.525 | 415.737 | 0.003 |
| VLF | 562.275 | 327.365 | 31.450 | 14.445 | 0.044 | 210.500 | 181.828 | 0.037 |
| LF | 216.450 | 154.426 | 47.325 | 33.125 | 0.080 | 226.250 | 231.452 | 0.909 |
| HF | 45.275 | 39.088 | 24.950 | 33.531 | 0.501 | 21.575 | 21.520 | 0.093 |
| LF Norm | 82.725 | 10.387 | 69.650 | 23.898 | 0.289 | 88.125 | 7.771 | 0.584 |
| HF Norm | 17.275 | 10.387 | 30.350 | 23.898 | 0.289 | 11.875 | 7.771 | 0.584 |
| LF/HF | 7.250 | 6.094 | 4.550 | 4.227 | 0.546 | 10.000 | 5.943 | 0.670 |
Discussion
The current study was designed to investigate the effect of exercise and custom-made flexible orthotics in athletes who perform exercise on regular basis over a 5-month period. The null hypothesis was that exercise and orthotics had no effect on BP and HRV. The study rejected the null hypothesis by demonstrating significant decreases in BP and HRV before, during, and after the exercise program with foot orthotics in the experimental group. No significant BP changes were observed in the control group. Significant increase in resting HRV was seen in the experimental group.
The reason behind selecting the 5-month study period was to allow the players to respond to the exercise program and the new orthotics to influence the autonomic nervous system activities. It has been reported by Loimaala et al,16 Perini et al,17 and Stein et al18 that short-term aerobic training had no effects on resting cardiac autonomic modulation in older people. A study by Iwasaki et al19 suggested a short-term positive effect of exercise training on HRV showing an increase at 3- and 6-month time points of regular training with an even decrease at 9 and 12 months. Uusitalo et al20 performed a 5-year study on exercise and HRV with 1 data collection per year. They found beneficial cardiovascular and autonomic effect.
Potential confounding factors, such as medication, diseases, and smoking, could have a strong effect on HRV and BP, which could cover the effect of physical activity and orthotics. In this study, all subjects were not taking any medications during the entire study period, none smoked cigarettes, and none had known cardiovascular diseases. In addition, all members of the current study performed the same level of exercise for at least 5 years, which reduced nonhomogeneity in their former activity levels. Because all subjects played the same sport during the study period, the effect of physical activity was more consistent than in a heterogeneous study16 of different levels and kinds of exercises. Therefore, all these factors strengthened the current study.
The present study used 5-minute ECG recording for HRV analysis, which was a short-term recording compared with 24-hour recording. Goldsmith et al21,22 measured 24-hour recordings, whereas others measure short recordings of at least 5 minutes. Some randomized longitudinal exercise training studies have used 24-hour HRV.16,23-25 There are only 2 randomized exercise training interventions using short-term HRV recordings reported.26,27 Among the randomized longitudinal studies,16,23-27 a positive effect of aerobic training on daytime HRV has been found in 3 studies,23-25 all using 24-hour recordings. In the other randomized studies, significant effects have not been found, even with a significant increase in maximal aerobic capacity. In addition, none of the randomized longitudinal studies found a significant effect on nighttime HRV. Some of the nonrandomized studies using short-term HRV recordings have found a positive effect of exercise training on HRV.19,28 Many studies have reported the changes of HRV in relation to athletic activities.29-35
Blood pressure was significantly decreased over the 5-month study period. This finding was not seen in the study of Uusitalo et al.20 Radaelli et al29 found an increase in sympathetic modulation of peripheral vessels with aerobic training in patients with chronic heart failure but not in healthy controls. Recent studies shown different response of moderate exercise training19 compared with heavy training in healthy athletes in BP variability.30 It has been hypothesized by researchers20 that BP changes associated with exercise training could result in vascular remodeling through adaptation of endothelium and smooth muscle19 rather than changes in vasomotor activity.
The orthotics seemed to assist players enhance the exercise program to achieve beneficial changes in BP and HRV. The significant BP decreases were only observed in the experimental group with orthotics. Because of the small sample size, the results were not conclusive. It only points to the positive direction for combing comfortable orthotics with an exercise program. In personal communication with club members, they all reported that the orthotics were comfortable to wear during exercise as well as during regular nonexercise period. This correlates with previously documented feedback.12-14,36,37 Because the orthotics used in the study were fitted into sports shoes, the break-in period was shortened for comfortable game wearing. There were 2 areas of improvement needed in the orthotics as noted by the participants. One suggestion was to use softer leather for athletic shoes for greater comfort and the second was to strengthen the shoe rubber adhesives, which loosened after 5 months of wear in 1 player's shoes.
The present study has some limitations. The most obvious was the small sample size, which was because of the small size of the sports club. Another factor that may potentially affect the results of the study was lack of blinding. This factor was minimized by using objective HRV analysis and reliable BP measurements. Another limitation is the cooling-off period used in the study for each day's final data collection. It was desirable to rest longer than 20 minutes after the final game to observe the return of HR to resting state. This answers the question of how much time is needed for a complete recovery from an exercise program. In this study, the exercise ended late at night, so it was impossible to extend the cooling period for the data collection sessions. Therefore, this 20-minute cooling-off period was chosen by compromise. It was noted in the study that many players' HR were still 10 to 30 beats higher than the resting baseline heartbeats.
Conclusion
The present randomized controlled pilot study of exercise and orthotics showed a significant decrease in BP and increase in HRV over the 5-month study period. The study demonstrated a potential benefit of combing exercise with orthotics to improve cardiovascular health in recreational athletes.
Acknowledgments
The custom-made shoe orthotics was provided free of charge to the subjects by Foot Levelers, Inc.
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