Skip to main content
Infection and Immunity logoLink to Infection and Immunity
. 1983 Aug;41(2):851–854. doi: 10.1128/iai.41.2.851-854.1983

Development and characterization of monoclonal antibodies to Marek's disease tumor-associated surface antigen.

X F Liu, L F Lee
PMCID: PMC264721  PMID: 6874076

Abstract

Four monoclonal antibodies, A35, B94, EB29, and G152, against Marek's disease tumor-associated surface antigen have been developed and their specificities studied against a panel of Marek's disease and lymphoid leukosis primary tumors; Marek's disease, and lymphoid leukosis, and reticuloendotheliosis lymphoblastoid cell lines; and normal chicken cells. A35 and G152 are of the immunoglobulin M class, and B94 and EB29 are of the immunoglobulin G1 subclass.

Full text

PDF
851

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Akiyama Y., Kato S. Two cell lines from lymphomas of Marek's disease. Biken J. 1974 Sep;17(3):105–116. [PubMed] [Google Scholar]
  2. Calnek B. W., Murthy K. K., Schat K. A. Establishment of Marek's disease lymphoblastoid cell lines from transplantable versus primary lymphomas. Int J Cancer. 1978 Jan 15;21(1):100–107. doi: 10.1002/ijc.2910210117. [DOI] [PubMed] [Google Scholar]
  3. Churchill A. E., Biggs P. M. Agent of Marek's disease in tissue culture. Nature. 1967 Jul 29;215(5100):528–530. doi: 10.1038/215528a0. [DOI] [PubMed] [Google Scholar]
  4. Greaves M. F., Brown G., Rapson N. T., Lister T. A. Antisera to acute lymphoblastic leukemia cells. Clin Immunol Immunopathol. 1975 May;4(1):67–84. doi: 10.1016/0090-1229(75)90041-0. [DOI] [PubMed] [Google Scholar]
  5. Hahn E. C., Ramos L., Kenyon A. J. Lymphoproliferative diseases of fowl: JM-V leukemic lymphoblasts in cell culture. J Natl Cancer Inst. 1977 Jul;59(1):267–271. doi: 10.1093/jnci/59.1.267. [DOI] [PubMed] [Google Scholar]
  6. Lee L. F., Liu X., Sharma J. M., Nazerian K., Bacon L. D. A monoclonal antibody reactive with Marek's disease tumor-associated surface antigen. J Immunol. 1983 Feb;130(2):1007–1011. [PubMed] [Google Scholar]
  7. Nazerian K., Elmubarak A., Sharma J. M. Establishment of B-lymphoblastoid cell lines from Marek's disease virus-induced tumors in turkeys. Int J Cancer. 1982 Jan 15;29(1):63–68. doi: 10.1002/ijc.2910290111. [DOI] [PubMed] [Google Scholar]
  8. Nazerian K., Solomon J. J., Witter R. L., Burmester B. R. Studies on the etiology of Marek's disease. II. Finding of a herpesvirus in cell culture. Proc Soc Exp Biol Med. 1968 Jan;127(1):177–182. doi: 10.3181/00379727-127-32650. [DOI] [PubMed] [Google Scholar]
  9. Nazerian K., Stephens E. A., Sharma J. M., Lee L. F., Gailitis M., Witter R. L. A nonproducer T lymphoblastoid cell line from Marek's disease transplantable tumor (JMV). Avian Dis. 1977 Jan-Mar;21(1):69–76. [PubMed] [Google Scholar]
  10. Nazerian K., Witter R. L., Crittenden L. B., Noori-Dalloii M. R., Kung H. J. An IgM-producing B lymphoblastoid cell line established from lymphomas induced by a non-defective reticuloendotheliosis virus. J Gen Virol. 1982 Feb;58(Pt 2):351–360. doi: 10.1099/0022-1317-58-2-351. [DOI] [PubMed] [Google Scholar]
  11. Powell P. C., Payne L. N., Frazier J. A., Rennie M. T lymphoblastoid cell lines from Marek's disease lymphomas. Nature. 1974 Sep 6;251(5470):79–80. doi: 10.1038/251079a0. [DOI] [PubMed] [Google Scholar]
  12. Schat K. A., Chen C. L., Shek W. R., Calnek B. W. Surface antigens on Marek's disease lymphoblastoid tumor cell lines. J Natl Cancer Inst. 1982 Sep;69(3):715–720. [PubMed] [Google Scholar]
  13. Sharma J. M., Coulson B. D. Cell-mediated cytotoxic response to cells bearing Marek's disease tumor-associated surface antigen in chickens infected with Marek's disease virus. J Natl Cancer Inst. 1977 Jun;58(6):1647–1651. doi: 10.1093/jnci/58.6.1647. [DOI] [PubMed] [Google Scholar]
  14. Witter R. L., Stephens E. A., Sharma J. M., Nazerian K. Demonstration of a tumor-associated surface antigen in Marek's disease. J Immunol. 1975 Jul;115(1):177–183. [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES