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. 1983 Jul;41(1):420–422. doi: 10.1128/iai.41.1.420-422.1983

Novel biological property of pertussis toxin: chemotactic activity on human monocytes.

T Ogawa, H Takada, S Kotani, H Sato, Y Sato
PMCID: PMC264795  PMID: 6305846

Abstract

Pertussis toxin isolated from Bordetella pertussis phase I strain Tohama enhanced the migration of human blood monocytes in an assay with a multiwell chemotaxis assembly. The monocyte migration enhancement by pertussis toxin was abolished by heating at 100 degrees C for 30 min, which caused a complete loss of the other biological activities of pertussis toxin. Checkerboard analysis demonstrated that the increased monocyte migration caused by pertussis toxin was directed toward a positive stimulus: chemotaxis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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