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. 1983 Jul;41(1):437–439. doi: 10.1128/iai.41.1.437-439.1983

Demonstration of antibodies to Mycoplasma pneumoniae attachment protein in human sera and respiratory secretions.

P C Hu, C H Huang, A M Collier, W A Clyde Jr
PMCID: PMC264800  PMID: 6862631

Abstract

Antibodies specific to the attachment protein of Mycoplasma pneumoniae were demonstrated in sera and respiratory secretions of human patients. The results indicate that the attachment protein is a major immunogen.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baseman J. B., Cole R. M., Krause D. C., Leith D. K. Molecular basis for cytadsorption of Mycoplasma pneumoniae. J Bacteriol. 1982 Sep;151(3):1514–1522. doi: 10.1128/jb.151.3.1514-1522.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Biberfeld G., Sterner G. Antibodies in bronchial secretions following natural infection with Mycoplasma pneumoniae. Acta Pathol Microbiol Scand B Microbiol Immunol. 1971;79(4):599–605. doi: 10.1111/j.1699-0463.1971.tb03818.x. [DOI] [PubMed] [Google Scholar]
  3. Brunner H., Chanock R. M. A radioimmunoprecipitation test for detection of Mycoplasma pneumoniae antibody. Proc Soc Exp Biol Med. 1973 May;143(1):97–105. doi: 10.3181/00379727-143-37261. [DOI] [PubMed] [Google Scholar]
  4. Collier A. M., Clyde W. A., Jr Appearance of Mycoplasma pneumoniae in lungs of experimentally infected hamsters and sputum from patients with natural disease. Am Rev Respir Dis. 1974 Dec;110(6):765–773. doi: 10.1164/arrd.1974.110.6P1.765. [DOI] [PubMed] [Google Scholar]
  5. Denny F. W., Clyde W. A., Jr, Glezen W. P. Mycoplasma pneumoniae disease: clinical spectrum, pathophysiology, epidemiology, and control. J Infect Dis. 1971 Jan;123(1):74–92. doi: 10.1093/infdis/123.1.74. [DOI] [PubMed] [Google Scholar]
  6. ENNY G. E., GRAYSTON J. T. EATON PLEUROPNEUMONIA-LIKE ORGANISM (MYCOPLASMA PNEUMONIAE) COMPLEMENT-FIXING ANTIGEN: EXTRACTION WITH ORGANIC SOLVENTS. J Immunol. 1965 Jul;95:19–25. [PubMed] [Google Scholar]
  7. Feldner J., Göbel U., Bredt W. Mycoplasma pneumoniae adhesin localized to tip structure by monoclonal antibody. Nature. 1982 Aug 19;298(5876):765–767. doi: 10.1038/298765a0. [DOI] [PubMed] [Google Scholar]
  8. Hu P. C., Cole R. M., Huang Y. S., Graham J. A., Gardner D. E., Collier A. M., Clyde W. A., Jr Mycoplasma pneumoniae infection: role of a surface protein in the attachment organelle. Science. 1982 Apr 16;216(4543):313–315. doi: 10.1126/science.6801766. [DOI] [PubMed] [Google Scholar]
  9. Hu P. C., Collier A. M., Baseman J. B. Surface parasitism by Mycoplasma pneumoniae of respiratory epithelium. J Exp Med. 1977 May 1;145(5):1328–1343. doi: 10.1084/jem.145.5.1328. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hu P. C., Huang Y. S., Graham J. A., Gardner D. E. Identification of immunogens of Mycoplasma pneumoniae by protein blotting. Biochem Biophys Res Commun. 1981 Dec 31;103(4):1363–1370. doi: 10.1016/0006-291x(81)90273-4. [DOI] [PubMed] [Google Scholar]
  11. Mogabgab W. J. Protective efficacy of killed Mycoplasma pneumoniae vaccine measured in large-scale studies in a military population. Am Rev Respir Dis. 1973 Oct;108(4):899–908. doi: 10.1164/arrd.1973.108.4.899. [DOI] [PubMed] [Google Scholar]
  12. Powell D. A., Clyde W. A., Jr Opsonin-reversible resistance of Mycoplasma pneumoniae to in vitro phagocytosis by alveolar macrophages. Infect Immun. 1975 Mar;11(3):540–550. doi: 10.1128/iai.11.3.540-550.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Sobeslavsky O., Prescott B., Chanock R. M. Adsorption of Mycoplasma pneumoniae to neuraminic acid receptors of various cells and possible role in virulence. J Bacteriol. 1968 Sep;96(3):695–705. doi: 10.1128/jb.96.3.695-705.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Taylor G., Taylor-Robinson D. Effects of active and passive immunization on Mycoplasma pulmonis-induced pneumonia in mice. Immunology. 1976 May;30(5):611–618. [PMC free article] [PubMed] [Google Scholar]
  15. Wenzel R. P., Craven R. B., Davies J. A., Hendley J. O., Hamory B. H., Gwaltney J. M., Jr Field trial of an inactivated Mycoplasma pneumoniae vaccine. I. Vaccine efficacy. J Infect Dis. 1976 Dec;134(6):571–576. doi: 10.1093/infdis/134.6.571. [DOI] [PubMed] [Google Scholar]

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