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. 1983 May;40(2):840–842. doi: 10.1128/iai.40.2.840-842.1983

Role of Phospholipase-Associated Penetration Mechanism in Cell Injury by Rickettsia rickettsii

David H Walker 1, William T Firth 1, J Glen Ballard 1, Barbara C Hegarty 1
PMCID: PMC264933  PMID: 6404837

Abstract

The cholesterol receptor-binding drugs amphotericin B and digitonin reduced rickettsial plaque formation, presumably by blocking rickettsial attachment, even when added to the plaque model on day 4 post-inoculation when infected foci were well established. The phospholipase inhibitor phentermine reduced plaque formation, presumably by inhibiting the phospholipase-associated entry step of penetration.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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