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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Immunity. 2009 Jan;30(1):21–32. doi: 10.1016/j.immuni.2008.10.018

Figure 3. A conserved surface in tapasin is important for PLC assembly/function.

Figure 3

(A) Space filling representation of tapasin/ERp57 with surface residues colored red/orange as in Figure 1B. For underlined residues, the side chain forms part of the protein core. The complex is oriented as in Figure 1A. (B) The complex has been rotated 180° around a vertical axis. (C) Residues that were mutated are colored (Table 2). Mutations that affect PLC assembly/function are colored in shades of red. Others are blue/green.