Skip to main content
NCBI home page
Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1992 Mar;30(3):716–718. doi: 10.1128/jcm.30.3.716-718.1992

Latex agglutination testing directly from throat swabs for rapid detection of beta-hemolytic streptococci from Lancefield serogroup C.

G F Hayden 1, J C Turner 1, D Kiselica 1, M Dunn 1, J O Hendley 1
PMCID: PMC265138  PMID: 1551989

Abstract

A latex agglutination method for the rapid detection of beta-hemolytic streptococci from Lancefield serogroup C in throat swabs from 403 university students with symptomatic pharyngitis was evaluated. Compared with culture, the rapid test was poorly sensitive (34.4%) but very specific (98.4%) in detecting group C beta-hemolytic streptococci. The sensitivity of the rapid test improved with an increasing quantity of growth on culture.

Full text

PDF
716

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Benjamin J. T., Perriello V. A., Jr Pharyngitis due to group C hemolytic streptococci in children. J Pediatr. 1976 Aug;89(2):254–256. doi: 10.1016/s0022-3476(76)80459-3. [DOI] [PubMed] [Google Scholar]
  2. Bucher C., von Graevenitz A. Differentiation in throat cultures of group C and G streptococci from Streptococcus milleri with identical antigens. Eur J Clin Microbiol. 1984 Feb;3(1):44–45. doi: 10.1007/BF02032818. [DOI] [PubMed] [Google Scholar]
  3. Cimolai N., Elford R. W., Bryan L., Anand C., Berger P. Do the beta-hemolytic non-group A streptococci cause pharyngitis? Rev Infect Dis. 1988 May-Jun;10(3):587–601. doi: 10.1093/clinids/10.3.587. [DOI] [PubMed] [Google Scholar]
  4. Corson A. P., Garagusi V. F., Chretien J. H. Group C beta-hemolytic streptococci causing pharyngitis and scarlet fever. South Med J. 1989 Sep;82(9):1119–1121. doi: 10.1097/00007611-198909000-00015. [DOI] [PubMed] [Google Scholar]
  5. Duca E., Teodorovici G., Radu C., Vî A., Talaşman-Niculescu P., Bernescu E., Feldi C., Roşca V. A new nephritogenic streptococcus. J Hyg (Lond) 1969 Dec;67(4):691–698. doi: 10.1017/s0022172400042145. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Facklam R. R. Specificity study of kits for detection of group A streptococci directly from throat swabs. J Clin Microbiol. 1987 Mar;25(3):504–508. doi: 10.1128/jcm.25.3.504-508.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Inzana T. J., Iritani B. Rapid detection of group C streptococci from animals by latex agglutination. J Clin Microbiol. 1989 Feb;27(2):309–312. doi: 10.1128/jcm.27.2.309-312.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Kaplan E. L. The rapid identification of group A beta-hemolytic streptococci in the upper respiratory tract. Current status. Pediatr Clin North Am. 1988 Jun;35(3):535–542. doi: 10.1016/s0031-3955(16)36470-7. [DOI] [PubMed] [Google Scholar]
  9. Lee P. C., Wetherall B. L. Cross-reaction between Streptococcus pneumoniae and group C streptococcal latex reagent. J Clin Microbiol. 1987 Jan;25(1):152–153. doi: 10.1128/jcm.25.1.152-153.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Meier F. A., Centor R. M., Graham L., Jr, Dalton H. P. Clinical and microbiological evidence for endemic pharyngitis among adults due to group C streptococci. Arch Intern Med. 1990 Apr;150(4):825–829. [PubMed] [Google Scholar]
  11. Petts D. N. Early detection of streptococci in swabs by latex agglutination before culture. J Clin Microbiol. 1984 Mar;19(3):432–433. doi: 10.1128/jcm.19.3.432-433.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Petts D. N., Lane A., Kennedy P., Hadfield S. G., McIllmurray M. B. Direct detection of groups A, C and G streptococci in clinical specimens by a trivalent colour test. Eur J Clin Microbiol Infect Dis. 1988 Feb;7(1):34–39. doi: 10.1007/BF01962168. [DOI] [PubMed] [Google Scholar]
  13. Radetsky M., Solomon J. A., Todd J. K. Identification of streptococcal pharyngitis in the office laboratory: reassessment of new technology. Pediatr Infect Dis J. 1987 Jun;6(6):556–563. doi: 10.1097/00006454-198706000-00014. [DOI] [PubMed] [Google Scholar]
  14. Ruch C. R., Beckwith D. G. Pharyngitis-tonsillitis in a college population. J Am Coll Health. 1984 Apr;32(5):222–226. doi: 10.1080/07448481.1984.10392812. [DOI] [PubMed] [Google Scholar]
  15. Schwartz R. H., Shulman S. T. Group C and group G streptococci. In-office isolation from children and adolescents with pharyngitis. Clin Pediatr (Phila) 1986 Oct;25(10):496–502. doi: 10.1177/000992288602501003. [DOI] [PubMed] [Google Scholar]
  16. Shlaes D. M., Toossi Z., Patel A. Comparison of latex agglutination and immunofluorescence for direct Lancefield grouping of streptococci from blood cultures. J Clin Microbiol. 1984 Aug;20(2):195–198. doi: 10.1128/jcm.20.2.195-198.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Turner J. C., Hayden G. F., Kiselica D., Lohr J., Fishburne C. F., Murren D. Association of group C beta-hemolytic streptococci with endemic pharyngitis among college students. JAMA. 1990 Nov 28;264(20):2644–2647. [PubMed] [Google Scholar]

Articles from Journal of Clinical Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES