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. 1992 Aug;30(8):2195–2199. doi: 10.1128/jcm.30.8.2195-2199.1992

Primary isolation of human T-cell leukemia-lymphoma virus types I and II: use for confirming infection in seroindeterminate blood donors.

B Hjelle 1, R Mills 1, C Goldsmith 1, S G Swenson 1, S Cyrus 1
PMCID: PMC265471  PMID: 1500534

Abstract

We describe the use of an immunofluorescence assay and coculture to confirm human T-cell leukemia-lymphoma virus (HTLV) infection. Peripheral blood mononuclear cells from 32 of 32 seropositive donors were positive in the immunofluorescence assay, and 63% of their cocultures produced p24 antigen. Specific antibodies distinguished HTLV type I (HTLV-I) from HTLV-II. HTLV-I or HTLV-II was isolated from donors with indeterminate serologic test results.

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Selected References

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