Skip to main content
. 2008 Oct 29;113(11):2442–2450. doi: 10.1182/blood-2008-05-157222

Figure 3.

Figure 3

Reversal of T-cell anergy after lymphodepletion and EBV-specific CTL infusion. (A) CD45 mAb-mediated lymphodepletion results in transient decrease of CD4+, CD25bright, and CD69− T cells (*P < .05). (B) The frequency of pentamer-positive and IFN-γ–secreting T cells specific for the HLA-A11–restricted EBNA3B peptide AVF were determined before lymphodepletion and 6 weeks after EBV-specific CTL infusion. Whereas the frequency of AVF-specific T cells was similar by pentamer analysis at both time points, AVF-specific T cells only secreted IFN-γ upon AVF peptide stimulation 6 weeks after CTL infusion.