Skip to main content
Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1993 Sep;31(9):2392–2395. doi: 10.1128/jcm.31.9.2392-2395.1993

Paecilomyces variotii in peritoneal dialysate.

A Marzec 1, L G Heron 1, R C Pritchard 1, R H Butcher 1, H R Powell 1, A P Disney 1, F A Tosolini 1
PMCID: PMC265767  PMID: 8408561

Abstract

Four cases of peritonitis caused by the filamentous fungus Paecilomyces variotii in patients on continuous ambulatory peritoneal dialysis are reported. Removal of the Tenckhoff catheter and antifungal chemotherapy led to resolution of symptoms in all cases. Possible contaminating events are discussed, and reported infections with P. variotii are reviewed.

Full text

PDF
2392

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ajello L. Hyalohyphomycosis and phaeohyphomycosis: two global disease entities of public health importance. Eur J Epidemiol. 1986 Dec;2(4):243–251. doi: 10.1007/BF00419488. [DOI] [PubMed] [Google Scholar]
  2. Bayer A. S., Blumenkrantz M. J., Montgomerie J. Z., Galpin J. E., Coburn J. W., Guze L. B. Candida peritonitis. Report of 22 cases and review of the English literature. Am J Med. 1976 Dec;61(6):832–840. doi: 10.1016/0002-9343(76)90407-1. [DOI] [PubMed] [Google Scholar]
  3. Castro L. G., Salebian A., Sotto M. N. Hyalohyphomycosis by Paecilomyces lilacinus in a renal transplant patient and a review of human Paecilomyces species infections. J Med Vet Mycol. 1990;28(1):15–26. [PubMed] [Google Scholar]
  4. Cecchin E., De Marchi S., Panarello G., Tesio F. Chemotherapy and/or removal of the peritoneal catheter in the management of fungal peritonitis complicating CAPD? Nephron. 1985;40(2):251–252. doi: 10.1159/000183473. [DOI] [PubMed] [Google Scholar]
  5. Cheng I. K., Fang G. X., Chan T. M., Chan P. C., Chan M. K. Fungal peritonitis complicating peritoneal dialysis: report of 27 cases and review of treatment. Q J Med. 1989 May;71(265):407–416. [PubMed] [Google Scholar]
  6. Crompton C. H., Balfe J. W., Summerbell R. C., Silver M. M. Peritonitis with Paecilomyces complicating peritoneal dialysis. Pediatr Infect Dis J. 1991 Nov;10(11):869–871. [PubMed] [Google Scholar]
  7. Dharmasena F. M., Davies G. S., Catovsky D. Paecilomyces varioti pneumonia complicating hairy cell leukaemia. Br Med J (Clin Res Ed) 1985 Mar 30;290(6473):967–968. doi: 10.1136/bmj.290.6473.967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Eisenberg E. S., Leviton I., Soeiro R. Fungal peritonitis in patients receiving peritoneal dialysis: experience with 11 patients and review of the literature. Rev Infect Dis. 1986 May-Jun;8(3):309–321. doi: 10.1093/clinids/8.3.309. [DOI] [PubMed] [Google Scholar]
  9. Fagerburg R., Suh B., Buckley H. R., Lorber B., Karian J. Cerebrospinal fluid shunt colonization and obstruction by Paecilomyces variotii. Case report. J Neurosurg. 1981 Feb;54(2):257–260. doi: 10.3171/jns.1981.54.2.0257. [DOI] [PubMed] [Google Scholar]
  10. Haldane E. V., MacDonald J. L., Gittens W. O., Yuce K., van Rooyen C. E. Prosthetic valvular endocarditis due to the fungus Paecilomyces. Can Med Assoc J. 1974 Nov 2;111(9):963-5, 968. [PMC free article] [PubMed] [Google Scholar]
  11. Harvey D. M., Sheppard K. J., Morgan A. G., Fletcher J. Effect of dialysate fluids on phagocytosis and killing by normal neutrophils. J Clin Microbiol. 1987 Aug;25(8):1424–1427. doi: 10.1128/jcm.25.8.1424-1427.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Henig F. E., Lehrer N., Gabbay A., Kurz O. Paecilomycosis of the lacrimal sac. Mykosen. 1973 Jan;16(1):25–28. doi: 10.1111/j.1439-0507.1973.tb04047.x. [DOI] [PubMed] [Google Scholar]
  13. Johnson R. J., Ramsey P. G., Gallagher N., Ahmad S. Fungal peritonitis in patients on peritoneal dialysis: incidence, clinical features and prognosis. Am J Nephrol. 1985;5(3):169–175. doi: 10.1159/000166928. [DOI] [PubMed] [Google Scholar]
  14. Kalish S. B., Goldschmidt R., Li C., Knop R., Cook F. V., Wilner G., Victor T. A. Infective endocarditis caused by Paecilomyces varioti. Am J Clin Pathol. 1982 Aug;78(2):249–252. doi: 10.1093/ajcp/78.2.249. [DOI] [PubMed] [Google Scholar]
  15. Kerr C. M., Perfect J. R., Craven P. C., Jorgensen J. H., Drutz D. J., Shelburne J. D., Gallis H. A., Gutman R. A. Fungal peritonitis in patients on continuous ambulatory peritoneal dialysis. Ann Intern Med. 1983 Sep;99(3):334–336. doi: 10.7326/0003-4819-99-3-334. [DOI] [PubMed] [Google Scholar]
  16. Kraus E. S., Spector D. A. Characteristics and sequelae of peritonitis in diabetics and nondiabetics receiving chronic intermittent peritoneal dialysis. Medicine (Baltimore) 1983 Jan;62(1):52–57. doi: 10.1097/00005792-198301000-00005. [DOI] [PubMed] [Google Scholar]
  17. McClellan J. R., Hamilton J. D., Alexander J. A., Wolfe W. G., Reed J. B. Paecilomyces varioti endocarditis on a prosthetic aortic valve. J Thorac Cardiovasc Surg. 1976 Mar;71(3):472–475. [PubMed] [Google Scholar]
  18. Otcenásek M., Jirousek Z., Nozicka Z., Mencl K. Paecilomycosis of the maxillary sinus. Mykosen. 1984 May;27(5):242–251. doi: 10.1111/j.1439-0507.1984.tb02025.x. [DOI] [PubMed] [Google Scholar]
  19. Peterson P. K., Matzke G., Keane W. F. Current concepts in the management of peritonitis in patients undergoing continuous ambulatory peritoneal dialysis. Rev Infect Dis. 1987 May-Jun;9(3):604–612. doi: 10.1093/clinids/9.3.604. [DOI] [PubMed] [Google Scholar]
  20. Pollock C. A., Ibels L. S., Caterson R. J., Mahony J. F., Waugh D. A., Cocksedge B. Continuous ambulatory peritoneal dialysis. Eight years of experience at a single center. Medicine (Baltimore) 1989 Sep;68(5):293–308. doi: 10.1097/00005792-198909000-00004. [DOI] [PubMed] [Google Scholar]
  21. Popovich R. P., Moncrief J. W., Nolph K. D., Ghods A. J., Twardowski Z. J., Pyle W. K. Continuous ambulatory peritoneal dialysis. Ann Intern Med. 1978 Apr;88(4):449–456. doi: 10.7326/0003-4819-88-4-449. [DOI] [PubMed] [Google Scholar]
  22. Prowant B., Nolph K., Ryan L., Twardowski Z., Khanna R. Peritonitis in continuous ambulatory peritoneal dialysis: analysis of an 8-year experience. Nephron. 1986;43(2):105–109. doi: 10.1159/000183807. [DOI] [PubMed] [Google Scholar]
  23. Rippon J. W., Larson R. A., Rosenthal D. M., Clayman J. Disseminated cutaneous and peritoneal hyalohyphomycosis caused by Fusarium species: three cases and review of the literature. Mycopathologia. 1988 Feb;101(2):105–111. doi: 10.1007/BF00452895. [DOI] [PubMed] [Google Scholar]
  24. Rubin J., Kirchner K., Walsh D., Green M., Bower J. Fungal peritonitis during continuous ambulatory peritoneal dialysis: a report of 17 cases. Am J Kidney Dis. 1987 Nov;10(5):361–368. doi: 10.1016/s0272-6386(87)80102-6. [DOI] [PubMed] [Google Scholar]
  25. Rubin J., Rogers W. A., Taylor H. M., Everett E. D., Prowant B. F., Fruto L. V., Nolph K. D. Peritonitis during continuous ambulatory peritoneal dialysis. Ann Intern Med. 1980 Jan;92(1):7–13. doi: 10.7326/0003-4819-92-1-7. [DOI] [PubMed] [Google Scholar]
  26. Saklayen M. G. CAPD peritonitis. Incidence, pathogens, diagnosis, and management. Med Clin North Am. 1990 Jul;74(4):997–1010. doi: 10.1016/s0025-7125(16)30532-6. [DOI] [PubMed] [Google Scholar]
  27. Sherwood J. A., Dansky A. S. Paecilomyces pyelonephritis complicating nephrolithiasis and review of Paecilomyces infections. J Urol. 1983 Sep;130(3):526–528. doi: 10.1016/s0022-5347(17)51287-2. [DOI] [PubMed] [Google Scholar]
  28. Silver M. D., Tuffnell P. G., Bigelow W. G. Endocarditis caused by Paecilomyces varioti affecting an aortic valve allograft. J Thorac Cardiovasc Surg. 1971 Feb;61(2):278–281. [PubMed] [Google Scholar]
  29. Swartz R. D. Chronic peritoneal dialysis: mechanical and infectious complications. Nephron. 1985;40(1):29–37. doi: 10.1159/000183423. [DOI] [PubMed] [Google Scholar]
  30. Tapson J. S., Mansy H., Freeman R., Wilkinson R. The high morbidity of CAPD fungal peritonitis--description of 10 cases and review of treatment strategies. Q J Med. 1986 Nov;61(235):1047–1053. [PubMed] [Google Scholar]
  31. Taylor P. C., Poole-Warren L. A., Grundy R. E. Increased microbial yield from continuous ambulatory peritoneal dialysis peritonitis effluent after chemical or physical disruption of phagocytes. J Clin Microbiol. 1987 Mar;25(3):580–583. doi: 10.1128/jcm.25.3.580-583.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Thompson R. F., Bode R. B., Rhodes J. C., Gluckman J. L. Paecilomyces variotii. An unusual cause of isolated sphenoid sinusitis. Arch Otolaryngol Head Neck Surg. 1988 May;114(5):567–569. doi: 10.1001/archotol.1988.01860170097028. [DOI] [PubMed] [Google Scholar]
  33. Thomson N. M., Atkins R. C., Humphery T. J., Agar J. M., Scott D. F. Continuous ambulatory peritoneal dialysis (CAPD): an established treatment for endstage renal failure. Aust N Z J Med. 1983 Oct;13(5):489–496. doi: 10.1111/j.1445-5994.1983.tb02700.x. [DOI] [PubMed] [Google Scholar]
  34. UYS C. J., DON P. A., SCHRIRE V., BARNARD C. N. ENDOCARDITIS FOLLOWING CARDIAC SURGERY DUE TO THE FUNGUS PAECILOMYCES. S Afr Med J. 1963 Dec 21;37:1276–1280. [PubMed] [Google Scholar]
  35. Wood G. M., McCormack J. G., Muir D. B., Ellis D. H., Ridley M. F., Pritchard R., Harrison M. Clinical features of human infection with Scedosporium inflatum. Clin Infect Dis. 1992 May;14(5):1027–1033. doi: 10.1093/clinids/14.5.1027. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES