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. 2009 Apr;11(4):408–417. doi: 10.1593/neo.81630

Figure 2.

Figure 2

Paroxetine and fluvoxamine did not decrease tumor growth. (A) Mice were injected s.c. with LLC on day 0 and were treated with saline (closed squares), paroxetine (circles), or fluvoxamine (open squares) from day 6, every 2fs days. (B) Mice were injected s.c. with KLN205 on day 0 and were treated with saline (closed squares), paroxetine (circles), or fluvoxamine (open squares) from day 6, every 2 days. Tumor volumes were calculated from tumor measurement scored on the indicated day. Results are presented as the mean tumor volume ± SD. (C, D) On day 23 (LLC) or 33 (KLN205) after implantation 5-HT in whole blood and tumors of mice with paroxetine, fluvoxamine, or saline. *Statistically significant (P < .05) compared with saline-treated mice. The values represent the mean ± SD (n = 8 per group).