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. 1987 Jan;25(1):146–149. doi: 10.1128/jcm.25.1.146-149.1987

Cytotoxic necrotizing factor production by hemolytic strains of Escherichia coli causing extraintestinal infections.

A Caprioli, V Falbo, F M Ruggeri, L Baldassarri, R Bisicchia, G Ippolito, E Romoli, G Donelli
PMCID: PMC265843  PMID: 3539987

Abstract

Two hundred and nineteen strains of Escherichia coli from extraintestinal infections and feces of healthy subjects were examined for hemolysin (Hly) and cytotoxic necrotizing factor (CNF) production and for mannose-resistant hemagglutination. Of 105 strains from extraintestinal infections, 42 (40.0%) were positive for production of both Hly and CNF, and 21 (20.0%) were positive for Hly alone; on the contrary, only 1 Hly- and CNF-positive strain and 2 Hly-positive strains were found among 114 strains from normal stools. CNF production was not found to occur among the nonhemolytic strains, confirming the close association existing between these toxic factors. Hemolytic strains positive for CNF showed mannose-resistant hemagglutination less frequently than did Hly-positive, CNF-negative strains (25.6 versus 82.6%), suggesting the existence of two distinct classes among hemolytic strains of E. coli.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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