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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1987 Mar;25(3):573–574. doi: 10.1128/jcm.25.3.573-574.1987

Rapid detection of group B streptococci directly from vaginal swabs.

E R Wald, B Dashefsky, M Green, J Harger, M Parise, C Korey, C Byers
PMCID: PMC265998  PMID: 3553229

Abstract

Duplicate vaginal swabs were obtained from patients who attended obstetric or gynecologic clinics affiliated with the Magee Womens Hospital in Pittsburgh. One swab was cultured semiquantitatively on 5% sheep blood agar to detect group B streptococci (GBS). The other swab was subjected to a rapid method (25 min) for antigen detection and micronitrous acid exposure to extract the GBS antigen, followed by latex particle agglutination. A total of 464 swabs were evaluated by direct plating. Fifty-two swabs (11.2%) were found to contain GBS. Overall, the rapid method detected 21 of 52, or 40.4%, positive specimens. The sensitivity of the rapid method for identifying the most heavily colonized samples was 85.7%. This method can be used to identify maternity patients who are heavily colonized with GBS and are at high risk of delivering septic infants.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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