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. 1988 Jan;26(1):133–135. doi: 10.1128/jcm.26.1.133-135.1988

Detection of antibody to cytomegalovirus-induced early antigens and comparison with four serologic assays and presence of viruria in blood donors.

E B Lentz 1, N L Dock 1, C A McMahon 1, S R Fiesthumel 1, C B Arnold 1, H V Lamberson Jr 1
PMCID: PMC266217  PMID: 2830297

Abstract

Five hundred blood donors were evaluated for cytomegalovirus (CMV) viruria, antibody to CMV early antigens (EA-ab), CMV seropositivity by two screening assays, and CMV-specific immunoglobulin M by two methods. Three donors were viruric, EA-ab positive, and seropositive; two viruric donors were immunoglobulin M positive.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adler S. P. Transfusion-associated cytomegalovirus infections. Rev Infect Dis. 1983 Nov-Dec;5(6):977–993. doi: 10.1093/clinids/5.6.977. [DOI] [PubMed] [Google Scholar]
  2. Bayer W. L., Tegtmeier G. E., Barbara J. A. The significance of non-A, non-B hepatitis, cytomegalovirus and the acquired immune deficiency syndrome in transfusion practice. Clin Haematol. 1984 Feb;13(1):253–269. [PubMed] [Google Scholar]
  3. Beneke J. S., Tegtmeier G. E., Alter H. J., Luetkemeyer R. B., Solomon R., Bayer W. L. Relation of titers of antibodies to CMV in blood donors to the transmission of cytomegalovirus infection. J Infect Dis. 1984 Dec;150(6):883–888. doi: 10.1093/infdis/150.6.883. [DOI] [PubMed] [Google Scholar]
  4. Chiba S., Motokawa T., Tamura T., Hanazono H., Kamada M., Chiba Y., Nakao T. Seroconversion to virus-specific pre-early nuclear antigens in infants with primary cytomegalovirus infection. Infect Immun. 1980 Oct;30(1):135–139. doi: 10.1128/iai.30.1.135-139.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Gerna G., Cereda P. M., Cattaneo E., Achilli G., Revello M. G. Immunoglobulin G to virus-specific early antigens in congenital, primary, and reactivated human cytomegalovirus infections. Infect Immun. 1978 Dec;22(3):833–841. doi: 10.1128/iai.22.3.833-841.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Griner P. F., Mayewski R. J., Mushlin A. I., Greenland P. Selection and interpretation of diagnostic tests and procedures. Principles and applications. Ann Intern Med. 1981 Apr;94(4 Pt 2):557–592. [PubMed] [Google Scholar]
  7. Kane R. C., Rousseau W. E., Noble G. R., Tegtmeier G. E., Wulff H., Herndon H. B., Chin T. D., Bayer W. L. Cytomegalovirus infection in a volunteer blood donor population. Infect Immun. 1975 Apr;11(4):719–723. doi: 10.1128/iai.11.4.719-723.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Krech U. Complement-fixing antibodies against cytomegalovirus in different parts of the world. Bull World Health Organ. 1973;49(1):103–106. [PMC free article] [PubMed] [Google Scholar]
  9. Middeldorp J. M., Jongsma J., ter Haar A., Schirm J., The T. H. Detection of immunoglobulin M and G antibodies against cytomegalovirus early and late antigens by enzyme-linked immunosorbent assay. J Clin Microbiol. 1984 Oct;20(4):763–771. doi: 10.1128/jcm.20.4.763-771.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Musiani M., Zerbini M., Carpi C., Plazzi M., Sermasi G., Belletti D., Sacchi R. Serological screening for the prevention of transfusion-acquired cytomegalovirus infection. J Infect. 1984 Sep;9(2):148–152. doi: 10.1016/s0163-4453(84)91078-8. [DOI] [PubMed] [Google Scholar]
  11. Onorato I. M., Morens D. M., Martone W. J., Stansfield S. K. Epidemiology of cytomegaloviral infections: recommendations for prevention and control. Rev Infect Dis. 1985 Jul-Aug;7(4):479–497. doi: 10.1093/clinids/7.4.479. [DOI] [PubMed] [Google Scholar]
  12. Pass R. F., Griffiths P. D., August A. M. Antibody response to cytomegalovirus after renal transplantation: comparison of patients with primary and recurrent infections. J Infect Dis. 1983 Jan;147(1):40–46. doi: 10.1093/infdis/147.1.40. [DOI] [PubMed] [Google Scholar]
  13. Stinski M. F. Sequence of protein synthesis in cells infected by human cytomegalovirus: early and late virus-induced polypeptides. J Virol. 1978 Jun;26(3):686–701. doi: 10.1128/jvi.26.3.686-701.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Tegtmeier G. E. Cytomegalovirus and blood transfusion. Prog Clin Biol Res. 1985;182:175–199. [PubMed] [Google Scholar]
  15. The T. H., Andersen H. K., Spencer E. S., Klein G. Antibodies against cytomegalovirus-induced early antigens (CMV-EA) in immunosuppressed renal-allograft recipients. Clin Exp Immunol. 1977 Jun;28(3):502–505. [PMC free article] [PubMed] [Google Scholar]
  16. The T. H., Klein G., Langenhuysen M. M. Antibody reactions to virus-specific early antigens (EA) in patients with cytomegalovirus (CMV) infection. Clin Exp Immunol. 1974 Jan;16(1):1-7,9-12. [PMC free article] [PubMed] [Google Scholar]

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