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. 1993 Nov;31(11):3075–3077. doi: 10.1128/jcm.31.11.3075-3077.1993

VP4 serotype of the Gottfried strain of porcine rotavirus.

B Li 1, M Gorziglia 1
PMCID: PMC266227  PMID: 8263206

Abstract

The antigenic relationships of the VP4 serotype of porcine rotavirus Gottfried strain with other rotaviruses were determined by using antiserum to Gottfried VP4-baculovirus recombinant. This antiserum failed to react significantly with virus of serotypes P1A, P1B, P3, and OSU; however, it reacted with P2 strains. In the reciprocal assay, antiserum to VP4 of an asymptomatic strain (P2) failed to neutralize the Gottfried strain virus to a significant level. It thus appears that the Gottfried strain should be considered a subtype of P2.

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Selected References

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  1. Bohl E. H., Theil K. W., Saif L. J. Isolation and serotyping of porcine rotaviruses and antigenic comparison with other rotaviruses. J Clin Microbiol. 1984 Feb;19(2):105–111. doi: 10.1128/jcm.19.2.105-111.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Estes M. K., Cohen J. Rotavirus gene structure and function. Microbiol Rev. 1989 Dec;53(4):410–449. doi: 10.1128/mr.53.4.410-449.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Gorziglia M., Nishikawa K., Hoshino Y., Taniguchi K. Similarity of the outer capsid protein VP4 of the Gottfried strain of porcine rotavirus to that of asymptomatic human rotavirus strains. J Virol. 1990 Jan;64(1):414–418. doi: 10.1128/jvi.64.1.414-418.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Greenberg H., McAuliffe V., Valdesuso J., Wyatt R., Flores J., Kalica A., Hoshino Y., Singh N. Serological analysis of the subgroup protein of rotavirus, using monoclonal antibodies. Infect Immun. 1983 Jan;39(1):91–99. doi: 10.1128/iai.39.1.91-99.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Kang S. Y., Saif L. J., Miller K. L. Reactivity of VP4-specific monoclonal antibodies to a serotype 4 porcine rotavirus with distinct serotypes of human (symptomatic and asymptomatic) and animal rotaviruses. J Clin Microbiol. 1989 Dec;27(12):2744–2750. doi: 10.1128/jcm.27.12.2744-2750.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Li B., Larralde G., Gorziglia M. Human rotavirus K8 strain represents a new VP4 serotype. J Virol. 1993 Jan;67(1):617–620. doi: 10.1128/jvi.67.1.617-620.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Liprandi F., Rodriguez I., Piña C., Larralde G., Gorziglia M. VP4 monotype specificities among porcine rotavirus strains of the same VP4 serotype. J Virol. 1991 Mar;65(3):1658–1661. doi: 10.1128/jvi.65.3.1658-1661.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Nishikawa K., Fukuhara N., Liprandi F., Green K., Kapikian A. Z., Chanock R. M., Gorziglia M. VP4 protein of porcine rotavirus strain OSU expressed by a baculovirus recombinant induces neutralizing antibodies. Virology. 1989 Dec;173(2):631–637. doi: 10.1016/0042-6822(89)90575-8. [DOI] [PubMed] [Google Scholar]
  9. Offit P. A., Clark H. F., Blavat G., Greenberg H. B. Reassortant rotaviruses containing structural proteins vp3 and vp7 from different parents induce antibodies protective against each parental serotype. J Virol. 1986 Nov;60(2):491–496. doi: 10.1128/jvi.60.2.491-496.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]

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