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. 1988 Jul;26(7):1411–1413. doi: 10.1128/jcm.26.7.1411-1413.1988

Identification of an antigen common to different species of the genus Campylobacter.

S D Mills 1, L A Kurjanczyk 1, J L Penner 1
PMCID: PMC266624  PMID: 2457601

Abstract

Affinity-purified antibody specific for a determinant on flagellin from Campylobacter jejuni was used to screen by immunoblotting strains of C. coli, C. laridis, C. fetus, "C. upsaliensis," C. pylori, and C. sputorum biovar fecalis. The antigen was detected in each of these species, but the molecular weights of the proteins bearing the common antigen varied considerably.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Blaser M. J., Duncan D. J. Human serum antibody response to Campylobacter jejuni infection as measured in an enzyme-linked immunosorbent assay. Infect Immun. 1984 May;44(2):292–298. doi: 10.1128/iai.44.2.292-298.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Goodwin C. S., McCulloch R. K., Armstrong J. A., Wee S. H. Unusual cellular fatty acids and distinctive ultrastructure in a new spiral bacterium (Campylobacter pyloridis) from the human gastric mucosa. J Med Microbiol. 1985 Apr;19(2):257–267. doi: 10.1099/00222615-19-2-257. [DOI] [PubMed] [Google Scholar]
  3. Harris L. A., Logan S. M., Guerry P., Trust T. J. Antigenic variation of Campylobacter flagella. J Bacteriol. 1987 Nov;169(11):5066–5071. doi: 10.1128/jb.169.11.5066-5071.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Jones D. M., Curry A., Fox A. J. An ultrastructural study of the gastric campylobacter-like organism 'Campylobacter pyloridis'. J Gen Microbiol. 1985 Sep;131(9):2335–2341. doi: 10.1099/00221287-131-9-2335. [DOI] [PubMed] [Google Scholar]
  5. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  6. Lee A., Logan S. M., Trust T. J. Demonstration of a flagellar antigen shared by a diverse group of spiral-shaped bacteria that colonize intestinal mucus. Infect Immun. 1987 Mar;55(3):828–831. doi: 10.1128/iai.55.3.828-831.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Logan S. M., Harris L. A., Trust T. J. Isolation and characterization of Campylobacter flagellins. J Bacteriol. 1987 Nov;169(11):5072–5077. doi: 10.1128/jb.169.11.5072-5077.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Mills S. D., Bradbury W. C. Human antibody response to outer membrane proteins of Campylobacter jejuni during infection. Infect Immun. 1984 Feb;43(2):739–743. doi: 10.1128/iai.43.2.739-743.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Mills S. D., Bradbury W. C., Penner J. L. Isolation and characterization of a common antigen in Campylobacter jejuni and Campylobacter coli. J Clin Microbiol. 1986 Jul;24(1):69–75. doi: 10.1128/jcm.24.1.69-75.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Nachamkin I., Hart A. M. Common and specific epitopes of Campylobacter flagellin recognized by monoclonal antibodies. Infect Immun. 1986 Aug;53(2):438–440. doi: 10.1128/iai.53.2.438-440.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Nachamkin I., Hart A. M. Western blot analysis of the human antibody response to Campylobacter jejuni cellular antigens during gastrointestinal infection. J Clin Microbiol. 1985 Jan;21(1):33–38. doi: 10.1128/jcm.21.1.33-38.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Penner J. L., Hennessy J. N., Congi R. V. Serotyping of Campylobacter jejuni and Campylobacter coli on the basis of thermostable antigens. Eur J Clin Microbiol. 1983 Aug;2(4):378–383. doi: 10.1007/BF02019474. [DOI] [PubMed] [Google Scholar]
  13. Rautelin H. I., Kosunen T. U. Campylobacter etiology in human gastroenteritis demonstrated by antibodies to acid extract antigen. J Clin Microbiol. 1987 Oct;25(10):1944–1951. doi: 10.1128/jcm.25.10.1944-1951.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Romaniuk P. J., Zoltowska B., Trust T. J., Lane D. J., Olsen G. J., Pace N. R., Stahl D. A. Campylobacter pylori, the spiral bacterium associated with human gastritis, is not a true Campylobacter sp. J Bacteriol. 1987 May;169(5):2137–2141. doi: 10.1128/jb.169.5.2137-2141.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Svedhem A., Gunnarsson H., Kaijser B. Diffusion-in-gel enzyme-linked immunosorbent assay for routine detection of IgG and IgM antibodies to Campylobacter jejuni. J Infect Dis. 1983 Jul;148(1):82–92. doi: 10.1093/infdis/148.1.82. [DOI] [PubMed] [Google Scholar]

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