Abstract
We report a case of fungemia and disseminated disease caused by a urease-negative strain of Cryptococcus neoformans in a patient with the acquired immune deficiency syndrome. Except for failure to hydrolyze urea, the microbiological characteristics of the isolate were typical of C. neoformans. Laboratory specialists should be aware of the occurrence of atypical strains of C. neoformans, particularly those recovered from patients with the acquired immune deficiency syndrome.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Kaplan W., Bragg S. L., Crane S., Ahearn D. G. Serotyping Cryptococcus neoformans by immunofluorescence. J Clin Microbiol. 1981 Sep;14(3):313–317. doi: 10.1128/jcm.14.3.313-317.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roberts G. D., Horstmeier C. D., Land G. A., Foxworth J. H. Rapid urea broth test for yeasts. J Clin Microbiol. 1978 Jun;7(6):584–588. doi: 10.1128/jcm.7.6.584-588.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Zimmer B. L., Roberts G. D. Rapid selective urease test for presumptive identification of Cryptococcus neoformans. J Clin Microbiol. 1979 Sep;10(3):380–381. doi: 10.1128/jcm.10.3.380-381.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Zuger A., Louie E., Holzman R. S., Simberkoff M. S., Rahal J. J. Cryptococcal disease in patients with the acquired immunodeficiency syndrome. Diagnostic features and outcome of treatment. Ann Intern Med. 1986 Feb;104(2):234–240. doi: 10.7326/0003-4819-104-2-234. [DOI] [PubMed] [Google Scholar]